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Fast-Track proposals will be accepted. Direct-to-Phase II proposals will NOT be accepted. Number of anticipated awards: 2-3 Budget (total costs): Phase I: $300,000 for up to one year; Phase II: $1,500,000 for up to 3 years Background There is an urgent need for new therapeutics products for treating pulmonary diseases caused by mycobacteria. These include tuberculosis (TB), caused by Mycobacterium ...

Fast-Track proposals will be accepted. Direct-to-Phase II proposals will NOT be accepted. Number of anticipated awards: 2-3 Budget (total costs): Phase I: $300,000 for up to one year; Phase II: $1,500,000 for up to 3 years. Background Diagnostics in current use for malaria and specific NTDs (visceral leishmaniasis, lymphatic filariasis, onchocerciasis, schistosomiasis) do not meet the sensitivity ...

(Direct to Phase II proposals will not be accepted) (Fast-Track proposals will be accepted) Number of anticipated awards: 1-2 Budget (total costs): Phase I: $300,000 for up to 1 year; Phase II: $1,500,000 for up to 3 years Page 118 Background Over 60 million people in the U.S. have genital herpes which is caused by infection with herpes simplex virus type 1 or 2 (HSV-1, HSV-2). The WHO’s 2021 gl ...

Fast-Track proposals will be accepted Direct-to-Phase II proposals will be accepted Number of anticipated awards: 2-3 Budget (total costs): Phase I: $300,000 for up to one year; Phase II: $1,500,000 for up to 3 years Background Injectable benzathine penicillin (BPG) is currently the only CDC-recommended first line therapy for treatment of infection with Treponema pallidum (syphilis) in all populat ...

Fast Track Proposals will be accepted. Direct-to-Phase II will be accepted. Number of anticipated awards: 1-3 Budget (total costs): Phase I: $ 300,000 for up to 1 year. Phase II: $ 1.5 million for up to 3 years. Page 120 Background The ability of innovative data science approaches to accelerate research on infectious and immune-mediated diseases highly depends on the availability of high-quality, ...

Fast Track Proposals will be accepted. Direct-to-Phase II will be accepted. Number of anticipated awards: 1-3 Budget (total costs): Phase I: $ 300,000 for up to 1 year. Phase II: $ 1.5 million for up to 3 years. Background Scientific research produces more data and knowledge than ever before and it is becoming increasingly challenging for researchers to digest and analyze the data to derive new kn ...

Budget and number of awards: Fast-Track proposals will be accepted. Direct-to-Phase II proposals will be accepted Number of anticipated awards: 1 Phase I, 1 Phase II Budget (total costs per award): Phase I: $350,000 for 12 months; Phase II: $3,000,000 for 2 years It is strongly suggested that proposals adhere to the above budget amounts and project periods. Proposals with budgets exceeding the abo ...

(Fast-Track and Direct to Phase 2 proposals will not be accepted) Number of anticipated awards: 1-3 Budget (total costs): Phase I: $300,000 for up to 1 year; Phase II: $2,000,000 for up to 2 years. Background According to the Centers for Disease Control and Prevention (CDC), HIV remains a significant public health challenge both in the United States and globally. In the United States, an estimated ...

(Fast-Track and Direct to Phase 2 proposals will not be accepted) Number of anticipated awards: 1-3 Budget (total costs): Phase I: $300,000 for up to 1 year; Phase II: $2,000,000 for up to 2 years. Background Central Nervous System complications associated with HIV continues to persist in people with HIV (PWH) despite effective Page 128 Antiretroviral therapy (ART). Although excellent virologic co ...

Phase I SBIR proposals will be accepted. Fast-Track proposals will not be accepted. Phase I clinical trials will not be accepted. Number of anticipated awards: 1 Budget (total costs): Phase I up to $243,500 for up to 6 months; Phase II of up to $1,927,828 and a Phase II duration of up to 2 years. PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Background Point ...