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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PAR-24-158: https://grants.nih.gov/grants/guide/PA-files/PAR-24-158.html

    Release Date: 02-29-2024Open Date: 03-05-2024 Due Dates: Multiple Close Date: 01-06-2027

    Introduction The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH), works to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. Translation is the process of turning observations in the ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. RFA-CA-24-022: SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)

    Release Date: 04-23-2024Open Date: 07-21-2024Due Date: 08-21-2024Close Date: 08-22-2024

    The Small Business Innovation Research (SBIR) Program is an important mechanism by which the National Institutes of Health (NIH) and other Federal agencies help bring innovative solutions to public health challenges. A major objective of the Federal SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of medical biote ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. PAR-24-131: Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed)

    Release Date: 04-26-2024Open Date: 08-05-2024 Due Dates: Multiple Close Date: 04-06-2027

    The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, also known as America's Seed Fund, are one of the largest sources of early-stage capital for technology commercialization in the United States. These programs enable US-owned and operated small businesses to conduct research and development that has a strong potential for commercialization. The Na ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. PAR-24-132: Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Required)

    Release Date: 04-26-2024Open Date: 08-05-2024 Due Dates: Multiple Close Date: 04-06-2027

    The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, also known as America's Seed Fund, are one of the largest sources of early-stage capital for technology commercialization in the United States. These programs enable US-owned and operated small businesses to conduct research and development that has a strong potential for commercialization. The Na ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  5. RFA-ES-24-003: SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)

    Release Date: 05-21-2024Open Date: 06-26-2024Due Date: 07-26-2024Close Date: 07-27-2024

    This SBIR NOFO focuses on the development of e-Learning health and safety training products from a variety of delivery methods to assist both students and instructors in the training and education process. Note that all products must be directly related to the health and safety training of workers exposed to hazardous materials (HAZMAT). Workers that may be exposed to these hazards include, but ar ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  6. A244-P017: xTechScalable AI 2

    Release Date: 10-03-2023Open Date: 03-11-2024Due Date: 03-31-2025Close Date: 11-18-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Artificial Intelligence/ Machine Learning; Trusted AI and Autonomy; Advanced Computing and Software; Human-Machine Interfaces OBJECTIVE: Topic 1: Scalable Tools for Automated AI Risk Management and Algorithmic Analysis As the Army deploys Artificial Intelligence (AI) systems, there is an inherent risk that the AI model could fail to perform as expe ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  7. A244-027: xTechSpecial Forces

    Release Date: 10-03-2023Open Date: 04-30-2024Due Date: 03-31-2025Close Date: 10-21-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy; Advanced Computing and Software; Integrated Sensing and Cyber; Microelectronics; Integrated Network Systems-of-Systems; Advanced Materials; Human-Machine Interfaces OBJECTIVE: Topic 1: GPS Denied ATAK Compatible Self Location Application The US Army 1st Special Forces Command (Airborne) is seeking a software solution to obt ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  8. SOCOM244-007 : Thermal Barrier Minimal Deflection Handguard

    Release Date: 10-03-2023Open Date: 05-06-2024Due Date: 03-31-2025Close Date: 06-24-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Future G; Advanced Materials; Human-Machine Interfaces OBJECTIVE: The objective of this topic is twofold. First, research thermodynamics involved in an over the suppressor handguard design. Secondly, designing a handguard with a toolless means of mounting. The Sig Sauer Rattler .300BO weapon system and the Sig Sauer SLH Suppressor is the host weapon asso ...

    SBIRPhase I/Phase IIDepartment of DefenseSpecial Operations Command
  9. SOCOM244-008: Ruggedized Additive Mobile Manufacturing Unit (RAMMU)

    Release Date: 10-03-2023Open Date: 05-06-2024Due Date: 03-31-2025Close Date: 06-24-2024

    OBJECTIVE: The objective of this topic is to develop applied research toward an innovative capability to use additive manufacturing in a deployed environment with the ability to decrease down time for foreign and non-standard weapons parts, motor pool parts, and dental accessories. IMPORTANT: For SOCOM instructions: please visit: https://www.defensesbirsttr.mil/SBIR-STTR/Opportunities/. Go ...

    SBIRPhase I/Phase IIDepartment of DefenseSpecial Operations Command
  10. A244-028: Software Defined RadioHead (SDRH)

    Release Date: 10-03-2023Open Date: 05-13-2024Due Date: 03-31-2025Close Date: 07-01-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Computing and Software; Integrated Network Systems-of-Systems OBJECTIVE: Develop a radio agnostic Software Defined RadioHead (SDRH) system with the capability to rapidly adapt the radio carrier frequency among diverse targeted frequency bands using analog and/or digital frequency conversion. Frequency translation of the original signal into a br ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
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