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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PAR-20-098: Non-Viral Technologies for in vivo Delivery of Genome Editors (R43/R44 Clinical Trial Not Allowed)

    Release Date: 02-06-2020Open Date: 03-05-2020 Due Dates: Multiple Close Date: 01-06-2022

    Research Objectives Maximizing the therapeutic impact of somatic genome editing requires the development of safe and effective technologies to deliver genome editing machinery into all disease-relevant somatic cells and tissues. Therefore, the objective of this FOA is to support the development and evaluation of innovative approaches to deliver genome editing machinery into somatic cells, with th ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. PA-19-076 : Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44 Clinical Trial Not Allowed)

    Release Date: 11-26-2018Open Date: 03-05-2019 Due Dates: Multiple Close Date: 01-05-2022

    Purpose This Funding Opportunity Announcement (FOA) invites applications that propose transformative engineering solutions to technical challenges associated with new development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. AA: Advanced Analytics (AA)

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    The Advanced Analytics topic focuses on innovations that involve the mathematical or computational analysis of data or statistics. This topic does not include learning-based systems, which are covered under the Artificial Intelligence (AI) topic. These subtopic areas are meant to serve as examples; all proposals with technical innovation and significant commercial potential are welcome, regardless ...

    SBIRPhase INational Science Foundation
  4. AA1: Data Collection, Cleaning, Integration and Processing

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AA1 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  5. AA2: Data Mining

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AA2 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  6. AA3: Decision Modelling

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AA3 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  7. AA4: Descriptive and Predictive Analytics

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AA4 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  8. AA5: Deterministic Modelling

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AA5 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  9. AA6: Optimization

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AA6 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  10. AA7: Simulation

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AA7 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
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