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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. N232-085: Autonomous Precision Landing onto Non-Cooperative Targets

    Release Date: 04-19-2023Open Date: 05-17-2023Due Date: 06-14-2023Close Date: 06-14-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Integrated Network Systems-of-Systems;Integrated Sensing and Cyber;Trusted AI and Autonomy The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export A ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  2. DL1: Autonomous Systems and Economies, and Smart Contracts

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  3. RFA-TR-22-029: Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases (U44 Clinical Trial Required)

    Release Date: 07-13-2022Open Date: 07-18-2022 Due Dates: Multiple Close Date: 07-13-2023

    A. Overview While there are thousands of rare diseases, the number of underlying etiologies is much smaller. Moreover, many disease etiologies underlie multiple traditional diseases. This is most readily seen for rare monogenic diseases, where the most common etiologies include premature termination codons, protein misfolding, and abnormal RNA splicing. Other examples of rare disease shared molec ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. MO1: Behavioral

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  5. CT1: Biochemicals

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  6. M2: Bio-Inspired Manufacturing

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  7. BT2: Bio-Inspired Technologies

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  8. BT3: Bioinstruments and Biosensors

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  9. BT: Biological Technologies (BT)

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    The Biological Technologies topic covers a wide range of technology areas to advance engineering and science innovation across the biological spectrum. Biological technologies have disrupted decades-old chemical, agricultural, and medical products and services, producing a new bioeconomy. Potential breakthroughs in this space are on course to make major socioeconomic contributions to the economy b ...

    SBIR/STTRPhase INational Science Foundation
  10. BM: Biomedical Technologies (BM)

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    The Biomedical Technologies topic aims to support the early-stage development of novel products, processes, or services that will enable the delivery of high-quality, economically-efficient healthcare. Subtopics are not aimed at supporting or conducting clinical trials, clinical efficacy or safety studies, the development pre-clinical or clinical-stage drug candidates or medical devices, or work p ...

    SBIR/STTRPhase INational Science Foundation
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