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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-ES-24-003: SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)

    Release Date: 05-21-2024Open Date: 06-26-2024Due Date: 07-26-2024Close Date: 07-27-2024

    This SBIR NOFO focuses on the development of e-Learning health and safety training products from a variety of delivery methods to assist both students and instructors in the training and education process. Note that all products must be directly related to the health and safety training of workers exposed to hazardous materials (HAZMAT). Workers that may be exposed to these hazards include, but ar ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. OSD244-P002: Development of novel 5G Open RAN (Radio Access Networks) xApp and rApp Applications Open Topic

    Release Date: 10-03-2023Open Date: 05-15-2024Due Date: 03-31-2025Close Date: 07-08-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): FutureG; Sustainment & Logistics OBJECTIVE: The Department of Defense (DoD) is seeking the development and demonstration of xApps and/or rApps focused on security and security related network measurement. DoD anticipates increasing reliance on 5G and FutureG OpenRAN networks, and needs tools and techniques that will enhance the security and resilience of ...

    SBIRPhase I/Phase IIDepartment of DefenseOffice of the Secretary of Defense
  3. RFA-DA-25-049: Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R41/R42- Clinical Trial Optional)

    Release Date: 06-13-2024Open Date: 11-02-2024Due Date: 12-02-2024Close Date: 12-03-2024

    Background Non-disordered drug use is defined as using a substance in the past year without meeting two or more Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) diagnostic criteria for a substance use disorder (SUD). Non-disordered drug use can have negative health consequences, including, but not limited to, an increased risk of drug (e.g., opioid, cannabis, synthetic ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. RFA-DA-25-050: Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R43/R44- Clinical Trial Optional)

    Release Date: 06-13-2024Open Date: 11-02-2024Due Date: 12-02-2024Close Date: 12-03-2024

    Background Non-disordered drug use is defined as using a substance in the past year without meeting two or more Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) diagnostic criteria for a substance use disorder (SUD). Non-disordered drug use can have negative health consequences, including, but not limited to, an increased risk of drug (e.g., opioid, cannabis, synthetic ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  5. PAR-24-221: NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)

    Release Date: 06-20-2024Open Date: 08-05-2024 Due Dates: Multiple Close Date: 04-06-2027

    Purpose NINDS is committed to advancing treatments, tools, and diagnostics that benefit people burdened by neurological diseases through the NINDS Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The SBIR/STTR Programs are structured in three phases. The main objective in SBIR/STTR Phase I is to establish the technical merit and feasibility of the ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
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