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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PA-20-047: Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed)

    Release Date: 01-08-2020Open Date: 03-05-2020 Due Dates: Multiple Close Date: 01-06-2023

    Background Single cell analysis has recently become an active area of research to uncover fundamental biological principles behind cell diversity, which are often masked and not amenable to the population analysis of cells. The past several years have witnessed a rapid advancement in the development of single cell technologies and analysis methods. Multiple single cell "-omics" approaches are eme ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. N212-120: Development of Non-Toxic but BioFouling Deterrent Marine Coatings

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): Autonomy;General Warfighting Requirements (GWR) TECHNOLOGY AREA(S): Ground / Sea Vehicles;Materials / Processes OBJECTIVE: Develop marine coatings that deter the settlement of biofouling without relying on the release of toxic chemicals. The coatings must not rely on an external source for activation (i.e., mechanical, optical, chemical) and must be practical for application ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  3. N212-136: Development of Predictive Aero-Optical Models of the Hypersonic Environment

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): Hypersonics;Space TECHNOLOGY AREA(S): Battlespace Environments;Information Systems;Weapons The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regul ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  4. CBD212-006: Development of Small Molecule Therapeutics Specifically Targeting Members of the Bunyavirales Order

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    KEY TECHNOLOGY AREA(S): Chemical/Biological Defense, Biomedical OBJECTIVE: Develop an antiviral drug to be used as a therapeutic in the event of disease or as a prophylactic medical countermeasure (MCM) following exposure or threat of exposure to viruses of the Bunyavirales order. DESCRIPTION: The Bunyaviridae are a very large family of single-strand, enveloped RNA viruses (more than 300 viru ...

    SBIRPhase I/Phase IIDepartment of DefenseOffice for Chemical and Biological Defense
  5. N212-D03: DIRECT TO PHASE II- Electrical Capacitors for High-Temperature Power Conversion

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): General Warfighting Requirements (GWR) TECHNOLOGY AREA(S): Electronics OBJECTIVE: Identify and demonstrate that advances in polymeric (or other film materials) dielectrics can be exploited in high temperature (150 °C–200 °C), compact, long life, highly reliable, electrical power capacitors in aircraft. DESCRIPTION: Electrification of naval aerospace platforms continues. ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  6. N212-D04: DIRECT TO PHASE II- High-Speed Digital Fiber Optic Receiver

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): General Warfighting Requirements (GWR);Networked C3 TECHNOLOGY AREA(S): Air Platforms The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  7. N212-D05: DIRECT TO PHASE II – Yield Increase for High-Performance Optical Interference Filters

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): General Warfighting Requirements (GWR) TECHNOLOGY AREA(S): Materials / Processes OBJECTIVE: Develop processing and manufacturing techniques to significantly improve the yield of high-performance optical interference filter systems, thus reducing unit cost. DESCRIPTION: Currently optical receiver systems use low to moderate performance interference filters to pass the desired ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  8. DTRA212-002: Distributed, Cooperative, Learning for Subterranean Robotic Autonomous Systems

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): Artificial Intelligence/ Machine Learning; Autonomy TECHNOLOGY AREA(S): Electronics; Sensors The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Reg ...

    SBIRPhase I/Phase IIDepartment of DefenseDefense Threat Reduction Agency
  9. MDA21-004: Dynamic Ballistic Missile Defense Three Dimensional (3-D) Combat Information Center Playback

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): Network Command, Control and Communications TECHNOLOGY AREA(S): Information Systems; Ground Sea; Space Platform; Weapons OBJECTIVE: Design, develop, and integrate a dynamic Missile Defense three-dimensional (3D) mission playback tool that can be used in the ship’s Combat Information Center (CIC). DESCRIPTION: The ability to process and visually display mission data within ...

    SBIRPhase I/Phase IIDepartment of DefenseMissile Defense Agency
  10. NGA212-002: Dynamic Parameter Selection for Community Detection Algorithms (Graph Networks)

    Release Date: 04-21-2021Open Date: 05-19-2021Due Date: 06-17-2021Close Date: 06-17-2021

    RT&L FOCUS AREA(S): INFORMATION SYSTEMS TECHNOLOGY AREA(S): AUTONOMY OBJECTIVE: Establish a general approach for dynamically setting the tuning parameter for a given community detection (CD) algorithm and graph. Validate the approach on four algorithms with novel data provided by the National Geospatial Intelligence Agency (NGA) . DESCRIPTION: NGA produces timely, accurate, and actionable geos ...

    SBIRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
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