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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PAR-21-282: Blueprint Medtech: Small Business Translator (U44- Clinical Trial Optional)

    Release Date: 08-20-2021Open Date: 09-20-2021 Due Dates: Multiple Close Date: 06-21-2024

    Blueprint MedTech The NIH Blueprint for Neuroscience Research is a collaborative framework through which 14 NIH Institutes, Centers and Offices jointly support neuroscience-related research, with the aim of accelerating discoveries and reducing the burden of nervous system disorders (for further information, see http://neuroscienceblueprint.nih.gov/). Innovators developing groundbreaking medical ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. A244-P001: xTech Search 8 SBIR Finalist Open Topic Competition

    Release Date: 10-03-2023Open Date: 10-16-2023Due Date: 03-31-2025Close Date: 06-12-2024

    OUSD (R&E) MODERNIZATION PRIORITY: AI/ML, Autonomy, General Warfighting Requirements (GWR) TECHNOLOGY AREA(S): Electronics, Human Systems, Sensors OBJECTIVE: xTechSearch is seeking novel, disruptive concepts and technology solutions with dual-use capabilities that can assist in tackling the Army’s current needs and apply to current Army concepts. The intent is to provide the Army with ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  3. A244-P019: Open Topic for Persistent Experimentation

    Release Date: 10-03-2023Open Date: 04-03-2024Due Date: 03-31-2025Close Date: 06-10-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Human-Machine Interfaces The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-774, which con ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  4. PAR-24-107: Solutions to Enable Regional Genomic Medicine eConsult Services (R41/R42 Clinical Trial Optional)

    Release Date: 01-09-2024Open Date: 04-30-2024Due Date: 05-30-2024Close Date: 05-31-2024

    Purpose This Notice of Funding Opportunity (NOFO) invites applications from eligible small businesses to develop solutions for commercialization that can be used to enable regional clinician-to-clinician genomic medicine eConsult services. Specifically, we seek products, such as technologies or services, that will allow for the development and sustainment of eConsult services. Eligible United Sta ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  5. PAR-24-106: Solutions to Enable Regional Genomic Medicine eConsult Services (R43/R44 Clinical Trial Optional)

    Release Date: 01-09-2024Open Date: 04-30-2024Due Date: 05-30-2024Close Date: 05-31-2024

    Purpose This Notice of Funding Opportunity (NOFO) invites applications from eligible small businesses to develop solutions for commercialization that can be used to enable regional clinician-to-clinician genomic medicine eConsult services. Specifically, we seek products, such as technologies or services, that will allow for the development and sustainment of eConsult services. Eligible United Sta ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  6. OSD244-001: Chief Digital and Artificial Intelligence Office (CDAO) Data Mesh Reference Design (REFDES)

    Release Date: 10-03-2023Open Date: 03-27-2024Due Date: 03-31-2025Close Date: 05-14-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Computing and Software; Integrated Network Systems-of-Systems OBJECTIVE: To break the Department of Defense (DoD) enterprise data out of stovepipes created for single use cases, and to make all data seamlessly interoperable across the department, while retaining federated control, hosting, and ownership. DESCRIPTION: The Department aims to ...

    SBIRPhase I/Phase IIDepartment of DefenseOffice of the Secretary of Defense
  7. 24.2-CSAI-1: Complete Streets AI Initiative: Generating, Integrating, and Activating Data for Mobility

    Release Date: 03-11-2024Open Date: 03-11-2024Due Date: 05-10-2024Close Date: 05-10-2024

    24.2-CSAI-1 FY24.2 DOT SBIR Solicitation Department of Transportation ...

    SBIRPhase IDepartment of Transportation
  8. 1: Topic L: Plant HYperaccumulators TO MIne Nickel-Enriched Soils (PHYTOMINES)

    Release Date: 03-21-2024Open Date: 03-21-2024Due Date: 05-07-2024Close Date: 05-07-2024

    1 Exploratory Topics SBIR/STTR: Plant HYperaccumulators TO MIne Nickel-Enriched Soils (PHYTOMINES) ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  9. A244-018: Tactical Implementation of Quantum Hardening

    Release Date: 10-03-2023Open Date: 03-05-2024Due Date: 03-31-2025Close Date: 04-23-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Quantum Science; Advanced Computing and Software; Integrated Network System of Systems The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120 – 130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Expor ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  10. A244-015: Novel Positioning, Navigation, and Timing (PNT) Signal Classification Techniques

    Release Date: 10-03-2023Open Date: 03-04-2024Due Date: 03-31-2025Close Date: 04-22-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted Artificial Intelligence (AI) and Autonomy; Integrated Sensing and Cyber OBJECTIVE: The purpose of this topic is to develop the capability to classify signals in real-time that impact navigation systems. The intent is to better understand the type(s) of signal(s) experienced in relevant environments to appropriately apply mitigation techniques be ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
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