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Mobile R/N detection systems are currently available to federal, state, and local authorities for purchase and deployment to detect R/N materials and related threats. These systems are sensitive and provide some indication of the direction from the detector to the threat but can't positively locate that threat. Law enforcement personnel have to leave their vehicles carrying hand-portable systems t ...

Effects of Space Weather --- Topic 9.5 Societal Challenge The effects of space weather pose significant and increasing societal, economic, national security, and health risks to the United States and nations worldwide. These include risks to the electric power grid; aviation operations; positioning, navigation, and timing (PNT) services; satellites and communications; human space exploration; and ...

According to the Centers for Disease Control and Prevention (CDC), more than 100,000 deaths from overdose were reported from April 2020 to April 2021 alone. Data shows an increase in overdoses due to natural and semi-synthetic opioids, synthetic opioids, predominantly fentanyl, and psychostimulants, such as methamphetamine or cocaine. In fact, in the year ending in April 2021, fentanyl was the lea ...

The DHS Science & Technology Directorate (S&T) laboratories and DHS component operational partners generate large volumes (up to 10,000 or more measurements per day) of data from test events, prototype demonstrations, or targeted stream of commerce (SoC) data collections. These data are incredibly valuable to DHS and our R&D partners to support the development of next-generation detection algorith ...

3 NIST FY 2024 Small Business Innovation Research (SBIR) Phase I NOFO Department of Commerce National Institute of Standards and Technology ...

Coastal Resilience --- Topic 9.2 Societal Challenge U.S. coastal communities, economies, and ecosystems, as well as the natural and built infrastructure on which they depend, are increasingly impacted by accelerating changes at the coast. Creating resilience to these changes requires risk-informed decision making and adaptation via enhanced emergency response, coastal data collection, and predic ...

A. Overview Recent advances in biology offer unprecedented opportunities to discover new treatments for nervous system disorders. Biotherapeutic development, however, has inherent complexities with regards to characterization, manufacturing, delivery, and administration. Many academic laboratories and small business enterprises don’t have the full scope of expertise and resources available; thi ...

A. Overview Recent advances in biology offer unprecedented opportunities to discover new treatments for nervous system disorders. Biotherapeutic development, however, has inherent complexities with regards to characterization, manufacturing, delivery, and administration. Many academic laboratories and small business enterprises don’t have the full scope of expertise and resources available; thi ...

Blueprint MedTech The NIH Blueprint for Neuroscience Research is a collaborative framework through which 14 NIH Institutes, Centers and Offices jointly support neuroscience-related research, with the aim of accelerating discoveries and reducing the burden of nervous system disorders (for further information, see http://neuroscienceblueprint.nih.gov/). Innovators developing groundbreaking medical ...

In 2021 and 2022, the number of U.S. overdose-related deaths topped 100,000, with about two-thirds of those attributed to synthetic opioids, mainly fentanyl. Fentanyl's chemical scaffold is easily tweaked to alter its spectroscopic signature and evade detection while delivering similar psychoactive effects. Numerous fentanyl analogues have been identified in illicit drug products and associated wi ...