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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. LC2: Collaborative Networking

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    LC2 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  2. PA-19-034 : Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R43/R44 Clinical Trial Not Allowed)

    Release Date: 10-24-2018Open Date: 12-05-2018 Due Dates: Multiple Close Date: 09-05-2021

    Background The human genome has revealed a great deal about the human proteome, though significant portions remain understudied. Only a subset of expressed proteins demonstrates the requisite properties to serve as targets for the development of therapeutics. Many bona fide drug targets likely remain to be discovered in the "Druggable Genome" (DG), which can be defined as a subset of the ~20,000 ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. PH3: Communications, Information, and Data Storage

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    PH3 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  4. CH2: Computational Architecture

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    CH2 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  5. BT6: Computational Biology and Bioinformatics

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    BT6 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  6. PAR-19-061 : Computational Genomics and Data Science Opportunities for Small Business (R43/R44 Clinical Trial Not Allowed)

    Release Date: 11-09-2018Open Date: 12-05-2018 Due Dates: Multiple Close Date: 09-05-2021

    Background Since its inception the field of genomics has been grounded in computational approaches. All facets of genomic research, such as processing raw sequencing signals, assembling genomes, calling variants, deriving insight from population sequencing studies, and designing and studying the implementation of genomics in clinical settings, are dependent upon computational, analytical, statist ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  7. ET1: Computational Sustainability

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    ET1 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  8. AV2: Computation and Data integration

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AV2 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  9. CA1: Computation on Encrypted Data

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    CA1 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  10. AI2: Computer Vision

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    AI2 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
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