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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PAR-23-069: HEAL Commercialization Readiness Pilot (CRP) Program: Embedded Entrepreneurs for Small Businesses in Pain Management (SB1 Clinical Trial Not Allowed)

    Release Date: 01-03-2023Open Date: 03-05-2023 Due Dates: Multiple Close Date: 09-06-2025

    The goal of this FOA is to support the commercialization of SBIR/STTR-funded pain management technologies through the addition of an experienced entrepreneur within small business leadership teams and by supporting private fundraising and partnership activities. This Commercialization Readiness Pilot (CRP) funding opportunity is specifically open to Small Business Innovation Research (SBIR) and Sm ...

    SBIR/STTRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. RFA-NS-23-006: HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)

    Release Date: 09-15-2022Open Date: 12-04-2022 Due Dates: Multiple Close Date: 04-05-2025

    Purpose The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. Specifically, this FOA is focused on applications directed at improving pain measurement ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. RFA-NS-23-007: HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)

    Release Date: 09-15-2022Open Date: 12-04-2022 Due Dates: Multiple Close Date: 04-05-2025

    Purpose The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Technology Transfer (STTR) program. Specifically, this FOA is focused on applications directed at improving pain measurement ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. A24B-T001: Hexavalent Chrome Replacement for Small Caliber Barrels

    Release Date: 04-17-2024Open Date: 05-15-2024Due Date: 06-12-2024Close Date: 06-12-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Materials The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-774, which controls ...

    STTRPhase IDepartment of DefenseArmy
  5. A24B-T003: High Reflector Microstructure for 1 Micron Continuous Wave Light and Mid to Long Wave Transmission

    Release Date: 04-17-2024Open Date: 05-15-2024Due Date: 06-12-2024Close Date: 06-12-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Directed Energy (DE), Space Technology, Advanced Materials OBJECTIVE: Build a microstructure designed for dielectric optically-transparent materials to act as a narrowband (1030 to 1070nm) high-reflector for cw laser light, while maintaining high transmission in the MWIR to LWIR. DESCRIPTION: There is a need to develop highly reflective microstructur ...

    STTRPhase IDepartment of DefenseArmy
  6. AF242-D017: High Resolution Low SWaP Attritable EO/IR Sensors for Stratospheric Operations

    Release Date: 04-17-2024Open Date: 05-15-2024Due Date: 06-12-2024Close Date: 06-12-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Integrated Sensing and Cyber; Emerging Threat Reduction; Integrated Network System-of-Systems OBJECTIVE: The objective of this topic is to develop a high resolution, low Size, Weight, and Power (SWaP), attritable, Electro-Optical/Infra-Red (EO/IR) sensor capable of detecting, tracking, and identifying targets with a National Imagery Interpretability Rati ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  7. A24B-T009: High Throughput, High Temperature Mechanical Test Platform

    Release Date: 04-17-2024Open Date: 05-15-2024Due Date: 06-12-2024Close Date: 06-12-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Hypersonics OBJECTIVE: Design, develop, and demonstrate a high-throughput mechanical test platform capable of replicating extreme thermal-mechanical-chemical environments. DESCRIPTION: The DoD requires robust, high temperature materials for a variety of extreme thermomechanical applications, including hypersonics, advanced propulsion, and next genera ...

    STTRPhase IDepartment of DefenseArmy
  8. AF242-D016: High Voltage Fireset/Electric Gun System Development

    Release Date: 04-17-2024Open Date: 05-15-2024Due Date: 06-12-2024Close Date: 06-12-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Computing and Software; Hypersonics; Advanced Materials The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulatio ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  9. PAR-24-158: https://grants.nih.gov/grants/guide/PA-files/PAR-24-158.html

    Release Date: 02-29-2024Open Date: 03-05-2024 Due Dates: Multiple Close Date: 01-06-2027

    Introduction The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH), works to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. Translation is the process of turning observations in the ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. AF242-D012: Humanoid Mobile Robot Manipulation Behavior Development

    Release Date: 04-17-2024Open Date: 05-15-2024Due Date: 06-12-2024Close Date: 06-12-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy; Integrated Sensing and Cyber; Human-Machine Interfaces OBJECTIVE: There is a clear AFSC and DoD need to automate our sustainment processes in order to improve safety, quality, capacity, and readiness. Our near peers are automating at an alarming rate, and we should be developing technologies that keep us as many steps ahead as po ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
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