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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-DA-24-018: Field-Deployable, Low-Cost Point-of-Need Approaches and Technologies to Lower the Barriers to Substance Use Disorders (SUD) Diagnosis and Treatment (R43/R44 Clinical Trial Optional)

    Release Date: 05-24-2023Open Date: 10-09-2023Due Date: 11-10-2023Close Date: 11-11-2023

    In 2020, 40.3 million people aged 12 or older had substance use disorder (SUD) in the past year. Of those, 2.6 million people (6.4%) received any in-person treatment, while 2.2 million (5.4%) received virtual services for substance use treatment. Therefore, an estimated 35 million people did not receive any treatment. To receive treatment, individuals need to receive a diagnosis from a provider, ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. RFA-DA-24-017: Field-Deployable, Low-Cost Point-of-Need Approaches and Technologies to Lower the Barriers to Substance Use Disorders (SUD) Diagnosis and Treatment (R41/R42 Clinical Trial Optional)

    Release Date: 05-24-2023Open Date: 10-09-2023Due Date: 11-09-2023Close Date: 11-10-2023

    In 2020, 40.3 million people aged 12 or older had substance use disorder (SUD) in the past year. Of those, 2.6 million people (6.4%) received any in-person treatment, while 2.2 million (5.4%) received virtual services for substance use treatment. Therefore, an estimated 35 million people did not receive any treatment. To receive treatment, individuals need to receive a diagnosis from a provider, ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. AF233-D010: Field-level Detection of Hydraulic Fluid Contamination in Jet Fuel

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Materials;Hypersonics OBJECTIVE: Develop for field and depot maintenance applications, an integrated, palm size analytical type instrument with control software application utilizing an Artificial Intelligence Deep Learning Algorithm that is capable of detecting, identifying, and quantifying by either percent by volume (vol%) ranging from 0.0 t ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  4. SF233-0011: Flexible Satellite Terminals for Multi-Tenancy Applications

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Microelectronics;Integrated Network System-of-Systems;Space Technology The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Reg ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  5. AF233-D011: Functional Gradient Coatings for Landing Gear

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Hypersonics;Microelectronics;Advanced Materials The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR P ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  6. AF233-D027: GPU Accelerated Large Eddy Simulation for Low Pressure Turbine Design

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy;Integrated Sensing and Cyber;Integrated Network System-of-Systems The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  7. AF233-D019: Hardened Scalar and Vector Magnetometer Development

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Integrated Sensing and Cyber;Trusted AI and Autonomy;Integrated Network System-of-Systems The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  8. RFA-NS-23-007: HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)

    Release Date: 09-15-2022Open Date: 12-04-2022 Due Dates: Multiple Close Date: 04-05-2025

    Purpose The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Technology Transfer (STTR) program. Specifically, this FOA is focused on applications directed at improving pain measurement ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  9. RFA-NS-23-006: HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)

    Release Date: 09-15-2022Open Date: 12-04-2022 Due Dates: Multiple Close Date: 04-05-2025

    Purpose The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. Specifically, this FOA is focused on applications directed at improving pain measurement ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. AF233-0025: High bandwidth, low latency wavefront sensing for airborne directed energy applications

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Directed Energy (DE) The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-774, which controls d ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
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