Open Topic Search

Reset

NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. NIH/NHLBI 105: Reagent Development for Small Cell Number ChIC-seq

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will not be accepted. Number of anticipated awards: 1 Budget (total costs): Phase I: $150,000 for 1 year It is strongly suggested that proposals adhere to the above budget amounts and project periods. Proposals with budgets exceeding the above amounts and project periods may not be funded. Summary This solicitation is for the development of conjugates between specific ant ...

    SBIR Department of Health and Human Services
  2. NIH/NIAID 050: Methods Improving HIV Protein Expression: Cell Substrate and Protein Purification

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Background Despite the widespread use of GMP-established pharma cell substrates (e.g., CHOs, 293 etc.) in development of recombinant HIV Env protein antigens, critical bottlenecks still exist in their use for large-scale, high-yield GMP manufacturing; yields often are on the order of mg/L compared to mAbs at gm/L. Some of the limitations relate to their intrinsic incapacities to metabolically pro ...

    SBIR Department of Health and Human Services
  3. NIH/NIAID 051: Inhaled Delivery of Clofazimine (CFZ) – An Important Anti-tuberculosis Drug

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast Track proposals will be accepted Number of anticipated awards: 2-3 Budget (total costs): Phase I: $300,000/year for up to2 years Phase II: $1,000,000/year for up to 3 years Background Development of improved drug regimens to shorten treatment for MDR and DS TB and improve tolerance and safety is an extremely high research priority. Clofazimine is a drug approved decades ago for treatment ...

    SBIR Department of Health and Human Services
  4. NIH/NIAID 052: High-Throughput Assay Platform for Quantifying Latent HIV Reservoirs

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted Number of anticipated awards: 1-2 Budget (total costs): Phase I: $300,000 for up to 1 year Phase II: $2,000,000 for up to 3 years Background One of the most significant hurdles to overcome in evaluating strategies to cure HIV infection is the lack of a simple method for quantifying changes in the size of the latent reservoir of replication-competent HIV in ...

    SBIR Department of Health and Human Services
  5. NIH/NIAID 053: Effective Targeted Delivery of RNA-based Vaccines and Therapeutics

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 1-2 Budget (total costs): Phase I: $300,000 for up to 1 year Phase II: $2,000,000 for up to 3 years Background RNA-based vaccines and therapeutics have emerged as great promise for HIV prevention and treatment, respectively. However, many obstacles still need to be overcome, in particular RNA instability, manufacturing proble ...

    SBIR Department of Health and Human Services
  6. NIH/NIAID 054: Adjuvant Discovery for Vaccines and for Autoimmune and Allergic Diseases

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 1-3 Budget (total costs): Phase I: $300,000/year for up to 2 years Phase II: $1,000,000/year for up to 3 years Background The goal of this program is to support the screening for new vaccine adjuvant candidates against infectious diseases or for toleragenic adjuvants for autoimmune or allergic diseases. Traditionally, adjuvan ...

    SBIR Department of Health and Human Services
  7. NIH/NIAID 055: Adjuvant Development for Vaccines and for Autoimmune and Allergic Diseases

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted Number of anticipated awards: 1-3 Budget (total costs): Phase I: $300,000/year for up to 2 years Phase II: $1,000,000/year for up to 3 years Background Adjuvants stimulate innate and/or adaptive immune responses. For the purpose of this SBIR, vaccine adjuvants are defined according to the U.S. Food and Drug Administration (FDA) as “agents added to, ...

    SBIR Department of Health and Human Services
  8. NIH/NIAID 056: Reagents for Immunologic Analysis of Non-mammalian Models

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted Number of anticipated awards: 1-3 Budget (total costs): Phase I: $300,000/year for up to 2 years Phase II: $1,000,000/year for up to 3 years Background This Funding Opportunity Announcement (FOA) is intended to address the limited availability of reagents (e.g., antibodies, proteins, ligands) for the identification and discrimination of immune cells of non ...

    SBIR Department of Health and Human Services
  9. NIH/NIAID 057: Development of Sample Sparing Assays

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 1-3 Budget (direct costs): Phase I: $300,000/year for up to 2 years Phase II: $1,000,000/year for up to 3 years Background The NIAID’s Division of Allergy, Immunology and Transplantation (DAIT) supports a wide range of research programs spanning basic immunology, translational and clinical research on protective immuni ...

    SBIR Department of Health and Human Services
  10. NIH/NIAID 058: Bioinformatics tools to make data FAIR (Findable, Accessible, Interoperable, and Re-usable)

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 1-2 Budget (total costs): Phase I: $300,000/year for up to 2 years Phase II: $1,000,000/year for up to 3 years Background The NIAID Division of Allergy, Immunology, and Transplantation (DAIT) has funded the following bioinformatics resources to meet the needs of the immunology research community for data sharing, knowledge di ...

    SBIR Department of Health and Human Services

Agency Micro-sites

US Flag An Official Website of the United States Government