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Background Currently, there are only three medications (four formulations) approved by the FDA for the treatment of alcohol use disorder (AUD). The need for additional medications to treat those affected by AUD is urgently needed.In addition,alcohol misuseaffects virtually all tissues and is linked with dysfunction and failure of many organs and systems including the liver, heart, pancreas, lung, ...

Background Currently, there are only three medications (four formulations) approved by the FDA for the treatment of alcohol use disorder (AUD). The need for additional medications to treat those affected by AUD is urgently needed.In addition,alcohol misuseaffects virtually all tissues and is linked with dysfunction and failure of many organs and systems including the liver, heart, pancreas, lung, ...

OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Quantum Science; Advanced Materials The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-774 ...

OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Materials OBJECTIVE: Research, evaluate, and ultimately deploy the ability to heat treat incrementally formed sheet metal parts directly on the forming equipment without removing the part. DESCRIPTION: Metal is typically formed in a soft state. After forming, the part is typically heat treated to make it harder and applicable for use on an a ...

Purpose This Funding Opportunity Announcement (FOA) invites eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I and Phase II (Fast track and Direct to phase II) grant applications. The funding opportunity will utilize a U43/U44 cooperative agreement to support SBCs to propose the development of novel extracellular vesicle-based therape ...

Purpose This Funding Opportunity Announcement (FOA) invites eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) Phase I and Phase II (Fast track) grant applications. The funding opportunity will utilize a UT1/UT2 cooperative agreement to support SBCs to propose the development of novel extracellular vesicle (EV)-based therapeutic platforms for ...

OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Computing and Software OBJECTIVE: Develop and demonstrate a data analysis tool methodology to capture relevant test parameters from past data into a usable form and create a digital engineering-level model capable of evaluating variables and providing accurate predictive answers. Models must be able to quickly learn from new data to improve pre ...

OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Space Technology The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-774, which controls du ...

OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Hypersonics; Integrated Sensing and Cyber; Advanced Materials OBJECTIVE: Develop and demonstrate a local Mach number or Static Pressure probe technology suitable for hypersonic and high enthalpy flows. DESCRIPTION: The Aerodynamic and Propulsion Test Unit (APTU) at the Arnold Engineering Development Complex (AEDC) is a high-speed hypersonic (HS/H) te ...

Purpose The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Technology Transfer (STTR) program. Specifically, this FOA is focused on applications directed at improving pain measurement ...