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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. A244-048: Lightweight AI-enabled image processing for Soldier-borne thermal imagers

    Release Date: 10-03-2023Open Date: 06-10-2024Due Date: 03-31-2025Close Date: 07-29-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy, Microelectronics, Integrated Sensing and Cyber, Advanced Computing and Software The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  2. A244-049: Algorithms for Modular Remote Expendable Sensor Array

    Release Date: 10-03-2023Open Date: 06-10-2024Due Date: 03-31-2025Close Date: 07-29-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Computing and Software, Integrated Network Systems-of-Systems, Integrated Sensing and Cyber The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  3. A244-050: Portable Diamond NV-Based Quantum Magnetometer for Enhanced Detection of Person-Borne Improvised Explosive Devices (PBIEDs)

    Release Date: 10-03-2023Open Date: 06-10-2024Due Date: 03-31-2025Close Date: 07-29-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Quantum Science, Trusted AI and Autonomy, Human-Machine Interfaces OBJECTIVE: To develop a portable, highly efficient Diamond Nitrogen-Vacancy (NV) Center-based Quantum Magnetometer, tailored specifically for detecting Person-Borne Improvised Explosive Devices (PBIEDs). DESCRIPTION: Quantum magnetometers, especially those utilizing Diamond Nitrogen-V ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  4. A244-051: Development of an Unmanned Aerial Systems (UAS) Passive Detection, Tracking, and Identification System for Ground Vehicles.

    Release Date: 10-03-2023Open Date: 06-10-2024Due Date: 03-31-2025Close Date: 07-29-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Integrated Sensing and Cyber OBJECTIVE: Develop a drone detection, tracking, and identification system using passive sensors. Develop a system for drone detection, tracking, and identification with low power consumption based on passive electronic devices that don’t radiate energy into surrounding environment. Energy harvesting sensors are possible. ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  5. A244-052: Dynamic Synthetic Tissues for Medical Simulation and Training

    Release Date: 10-03-2023Open Date: 06-10-2024Due Date: 03-31-2025Close Date: 07-29-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Biotechnology, Advanced Materials OBJECTIVE: Develop a material-based solution which can demonstrate prolonged casualty care (PCC), nursing care, and trauma scenarios while dynamically changing the patient state based on the care being provided. DESCRIPTION: Human patient simulators leverage unreliable mechanical air bladders, anatomically inaccurate ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  6. A244-053: Automated and Modular Forward Deployed Biomanufacturing Unit for Warfighter Field Feeding at Point of Need

    Release Date: 10-03-2023Open Date: 06-10-2024Due Date: 03-31-2025Close Date: 07-29-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Biotechnology OBJECTIVE: Advance research that safely produces nutritious foodstuffs via biosynthesis at point of need to overcome contested logistics and sustain the future force with high quality nutrition on-demand that ensures food security DESCRIPTION: Point of need (PON) food production may sustain units deployed in contested logistics (CL) env ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  7. RFA-ES-24-003: SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)

    Release Date: 05-21-2024Open Date: 06-26-2024Due Date: 07-26-2024Close Date: 07-27-2024

    This SBIR NOFO focuses on the development of e-Learning health and safety training products from a variety of delivery methods to assist both students and instructors in the training and education process. Note that all products must be directly related to the health and safety training of workers exposed to hazardous materials (HAZMAT). Workers that may be exposed to these hazards include, but ar ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  8. RFA-DA-25-054: Harnessing Artificial Intelligence and Polypharmacology to Discover Pharmacotherapeutics for Substance Use Disorders (R43/R44 Clinical Trials Not Allowed)

    Release Date: 01-29-2024Open Date: 06-25-2024Due Date: 07-25-2024Close Date: 07-26-2024

    Background: Drug discovery and development is a high-cost, high-risk, and time-consuming endeavor where the failure rate of therapeutic candidates that enter clinical trials is 90%. Because of this, in recent years, artificial intelligence (AI), including machine learning ( ML) technologies, has been embraced to reduce clinical failure rates and to speed up drug discovery. AI/ML technologies are ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  9. RFA-DA-25-053: Harnessing Artificial Intelligence and Polypharmacology to Discover Pharmacotherapeutics for Substance Use Disorders (R41/R42 Clinical Trials Not Allowed)

    Release Date: 01-29-2024Open Date: 06-25-2024Due Date: 07-25-2024Close Date: 07-26-2024

    Background: Drug discovery and development is a high-cost, high-risk, and time-consuming endeavor where the failure rate of therapeutic candidates that enter clinical trials is 90%. Because of this, in recent years, artificial intelligence (AI), including machine learning (ML) technologies, has been embraced to reduce clinical failure rates and to speed up drug discovery. AI/ML technologies are u ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. OSD244-P002: Development of novel 5G Open RAN (Radio Access Networks) xApp and rApp Applications Open Topic

    Release Date: 10-03-2023Open Date: 05-15-2024Due Date: 03-31-2025Close Date: 07-08-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): FutureG; Sustainment & Logistics OBJECTIVE: The Department of Defense (DoD) is seeking the development and demonstration of xApps and/or rApps focused on security and security related network measurement. DoD anticipates increasing reliance on 5G and FutureG OpenRAN networks, and needs tools and techniques that will enhance the security and resilience of ...

    SBIRPhase I/Phase IIDepartment of DefenseOffice of the Secretary of Defense
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