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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. N244-P03: NAVWAR Open Topic for Advanced Data Integrity and Control Methods

    Release Date: 10-03-2023Open Date: 06-12-2024Due Date: 03-31-2025Close Date: 09-03-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Integrated Network Systems of Systems The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-7 ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  2. RFA-DA-25-050: Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R43/R44- Clinical Trial Optional)

    Release Date: 06-13-2024Open Date: 11-02-2024Due Date: 12-02-2024Close Date: 12-03-2024

    Background Non-disordered drug use is defined as using a substance in the past year without meeting two or more Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) diagnostic criteria for a substance use disorder (SUD). Non-disordered drug use can have negative health consequences, including, but not limited to, an increased risk of drug (e.g., opioid, cannabis, synthetic ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. PAR-24-221: NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)

    Release Date: 06-20-2024Open Date: 08-05-2024 Due Dates: Multiple Close Date: 04-06-2027

    Purpose NINDS is committed to advancing treatments, tools, and diagnostics that benefit people burdened by neurological diseases through the NINDS Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The SBIR/STTR Programs are structured in three phases. The main objective in SBIR/STTR Phase I is to establish the technical merit and feasibility of the ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
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