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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PAR-24-107: Solutions to Enable Regional Genomic Medicine eConsult Services (R41/R42 Clinical Trial Optional)

    Release Date: 01-09-2024Open Date: 04-30-2024Due Date: 05-30-2024Close Date: 05-31-2024

    Purpose This Notice of Funding Opportunity (NOFO) invites applications from eligible small businesses to develop solutions for commercialization that can be used to enable regional clinician-to-clinician genomic medicine eConsult services. Specifically, we seek products, such as technologies or services, that will allow for the development and sustainment of eConsult services. Eligible United Sta ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. A244-018: Tactical Implementation of Quantum Hardening

    Release Date: 10-03-2023Open Date: 03-05-2024Due Date: 03-31-2025Close Date: 04-23-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Quantum Science; Advanced Computing and Software; Integrated Network System of Systems The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120 – 130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Expor ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  3. RFA-MD-24-007: Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)

    Release Date: 03-08-2024Open Date: 05-10-2024 Due Dates: Multiple Close Date: 12-10-2026

    Background Despite continued improvement in the health of the U.S. population with the introduction of medical and scientific advances, there continues to be an alarming disproportionate burden of illness among certain population groups. The mission of the NIMHD is to lead scientific research aimed at the development of innovative diagnostics, treatments, and prevention strategies to improve mino ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. A244-013: User and Entity Behavior Analysis

    Release Date: 10-03-2023Open Date: 01-31-2024Due Date: 03-31-2025Close Date: 03-19-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Integrated Network Systems-of-Systems OBJECTIVE: This User and Entity Behavioral Analysis (UEBA) will streamline authentication to the network and services while transparently securing mission critical services such a warfighting applications, through granular role-based access control. As implemented, this UEBA solution will be a critical enabler to the ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  5. A244-P006: xTechScalable AI

    Release Date: 10-03-2023Open Date: 01-03-2024Due Date: 03-31-2025Close Date: 04-17-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy; Advanced Computing and Software; Human-Machine Interfaces OBJECTIVE: xTechScalable AI is seeking novel, disruptive concepts and technology solutions that can assist in tackling the Army’s current needs and apply to current Army concepts. Current Machine Learning pipelines are vulnerable to manipulation of code, data, labels, and ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  6. A244-P017: xTechScalable AI 2

    Release Date: 10-03-2023Open Date: 03-11-2024Due Date: 03-31-2025Close Date: 11-18-2024

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Artificial Intelligence/ Machine Learning; Trusted AI and Autonomy; Advanced Computing and Software; Human-Machine Interfaces OBJECTIVE: Topic 1: Scalable Tools for Automated AI Risk Management and Algorithmic Analysis As the Army deploys Artificial Intelligence (AI) systems, there is an inherent risk that the AI model could fail to perform as expe ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  7. A244-P001: xTech Search 8 SBIR Finalist Open Topic Competition

    Release Date: 10-03-2023Open Date: 10-16-2023Due Date: 03-31-2025Close Date: 06-12-2024

    OUSD (R&E) MODERNIZATION PRIORITY: AI/ML, Autonomy, General Warfighting Requirements (GWR) TECHNOLOGY AREA(S): Electronics, Human Systems, Sensors OBJECTIVE: xTechSearch is seeking novel, disruptive concepts and technology solutions with dual-use capabilities that can assist in tackling the Army’s current needs and apply to current Army concepts. The intent is to provide the Army with ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
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