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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

Displaying 1 - 10 of 469 results
  1. PAR-17-201 : Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44)

    Release Date: 03-09-2017Open Date: 07-09-2017 Due Dates: Multiple Close Date: 05-07-2020

    A. Overview Recent advances in neuroscience offer unprecedented opportunities to discover new treatments for nervous system disorders. However, before a new chemical entity can be tested in a clinical setting, it must undergo a process of chemical optimization to improve potency, selectivity, and drug-like properties, followed by pre-clinical safety testing to meet the standards set by the Food an ...

    SBIR Department of Health and Human Services
  2. PAR-17-108: Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R43/R44)

    Release Date: 01-09-2017Open Date: 03-05-2017 Due Dates: Multiple Close Date: 04-05-2020

    The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Innovation Research (SBIR) research and development of next-generation socially-assistive robots (SARs) to enhance health and well-being, reduce illness and disability, and improve quality of life for individuals with Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD), and for caregiver ...

    SBIR Department of Health and Human Services
  3. PAR-17-107 : Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R41/R42)

    Release Date: 01-09-2017Open Date: 03-05-2017 Due Dates: Multiple Close Date: 04-05-2020

    The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Technology Transfer (STTR) research and development of next-generation socially-assistive robots (SARs) to enhance health and well-being, reduce illness and disability, and improve quality of life for individuals with Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD), and for caregiver ...

    STTR Department of Health and Human Services
  4. PA-16-451: Kidney Precision Medicine Project- Technology Development and Validation (R41/R42)

    Release Date: 09-28-2016Open Date: 12-05-2016 Due Dates: Multiple Close Date: 01-05-2020

    Background Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD) impose a significant global health burden. Yet, no effective therapies currently exist for AKI, and only a few are available for CKD. Community feedback indicates that—despite significant effort from industry and academia—development of pharmacologic therapies for AKI and CKD has been hampered by non-predictive animal models ...

    STTR Department of Health and Human Services
  5. PA-16-452: Kidney Precision Medicine Project- Technology Development and Validation (R43/R44)

    Release Date: 09-28-2016Open Date: 12-05-2016 Due Dates: Multiple Close Date: 01-05-2020

    Background Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD) impose a significant global health burden. Yet, no effective therapies currently exist for AKI, and only a few are available for CKD. Community feedback indicates that—despite significant effort from industry and academia—development of pharmacologic therapies for AKI and CKD has been hampered by non-predictive animal models ...

    SBIR Department of Health and Human Services
  6. PAS-17-023 : Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R41/R42)

    Release Date: 10-19-2016Open Date: 12-05-2016 Due Dates: Multiple Close Date: 01-05-2020

    Purpose This Funding Opportunity Announcement (FOA) supports Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that will develop and/or validate devices or electronic systems that can: 1) monitor biologically- or behaviorally-based processes applicable to mind and body interventions or 2) be used to assist in optimizing the practice or increasing the ...

    STTR Department of Health and Human Services
  7. PAS-17-022 : Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R43/R44)

    Release Date: 10-19-2016Open Date: 12-05-2016 Due Dates: Multiple Close Date: 01-05-2020

    Purpose The National Center for Complementary and Integrative Health (NCCIH) is committed to the rigorous investigation of mind and body interventions to determine their usefulness and safety.   Through this FOA, NCCIH supports cutting-edge Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that will develop and/or validate devices or electro ...

    SBIR Department of Health and Human Services
  8. PA-17-130: Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R43/R44)

    Release Date: 01-24-2017Open Date: 03-05-2017 Due Dates: Multiple Close Date: 01-05-2020

    Background Recent significant advances in genetics, the basic understanding of physiology, and the pathogenesis of disease coupled with technological advances in areas such as bioinformatics, chemical biology, synthetic chemistry, and protein engineering have provided a rich knowledge base and strong toolbox to identify and pursue new drug targets with the goal of generating new molecular therapie ...

    SBIR Department of Health and Human Services
  9. PA-17-131 : Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R41/R42)

    Release Date: 01-24-2017Open Date: 03-05-2017 Due Dates: Multiple Close Date: 01-05-2020

    Background Recent significant advances in genetics, the basic understanding of physiology, and the pathogenesis of disease coupled with technological advances in areas such as bioinformatics, chemical biology, synthetic chemistry, and protein engineering have provided a rich knowledge base and strong toolbox to identify and pursue new drug targets with the goal of generating new molecular therapie ...

    STTR Department of Health and Human Services
  10. PA-17-147 : Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44)

    Release Date: 02-01-2017Open Date: 03-05-2017 Due Dates: Multiple Close Date: 01-05-2020

    Background Single cell analysis has recently become an active area of research to uncover fundamental biological principles behind cell diversity, which are often masked and not amenable to the population analysis of cells. The past several years have witnessed a rapid advancement in the development of single cell technologies and analysis methods. Multiple single cell "-omics" approaches are emer ...

    SBIR Department of Health and Human Services

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