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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PA-18-709: Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42 Clinical Trial Not Allowed)

    Release Date: 03-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 09-05-2021

    Background G-protein coupled receptor proteins (GPCRs) are membrane bound proteins that serve to modulate cellular activities. Many of the GPCRs have potential significance in healthy mental function and in mental disorders, including receptors for most neurotransmitters and neuropeptides. Drugs targeting GPCRs are currently used in the treatment of mental disorders such as schizophrenia, ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  2. PA-18-708 : Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)

    Release Date: 03-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 09-05-2021

    Background G-protein coupled receptor proteins (GPCRs) are membrane bound proteins that serve to modulate cellular activities. Many of the GPCRs have potential significance in healthy mental function and in mental disorders, including receptors for most neurotransmitters and neuropeptides. Drugs targeting GPCRs are currently used in the treatment of mental disorders such as schizophrenia, anxie ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  3. PA-18-705 : SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)

    Release Date: 03-06-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    The SBIR Technology Transfer (SBIR-TT) Funding Opportunity Announcement (FOA) is intended to help move commercially-viable technologies from the NIH Intramural Program to the marketplace. Small Business Concerns (SBCs) are encouraged to submit applications that further develop available technologies from the NIH Intramural Program and bring them to the commercial market. While universities can spi ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  4. PA-18-786 : Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)

    Release Date: 05-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  5. PA-18-785 : Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)

    Release Date: 05-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  6. PA-18-816 : Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42- Clinical Trial Not Allowed)

    Release Date: 06-05-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Fetal bovine serum (FBS) is the most widely used growth supplement for cell culture; it cost-effectively supports the survival, growth, and differentiation of many cell lines by providing nutrients, growth signals, and protection from stress. Although serum is an effective growth promoter, it is variable in its composition, activity, and effects on cellular phenotypes. This variability introduces ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  7. PA-18-815 : Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44- Clinical Trial Not Allowed)

    Release Date: 06-05-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Fetal bovine serum (FBS) is the most widely used growth supplement for cell culture; it cost-effectively supports the survival, growth, and differentiation of many cell lines by providing nutrients, growth signals, and protection from stress. Although serum is an effective growth promoter, it is variable in its composition, activity, and effects on cellular phenotypes. This variability introduces ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  8. PAR-18-632 : NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)

    Release Date: 02-06-2018Open Date: 04-14-2018 Due Dates: Multiple Close Date: 01-13-2021

    Purpose This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to implement investigator-initiated clinical trials. A clinical trial is defined by NIH as: "A research study in which one or more human subjects are prospectively assigned to one or more interventions  ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  9. PAR-18-779: Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed)

    Release Date: 05-09-2018Open Date: 09-02-2018 Due Dates: Multiple Close Date: 01-07-2021

    This Funding Opportunity Announcement (FOA) seeks small business grant applications to develop major advances in genomic technologies. Advances in basic research, clinical applications of genomics and more broadly in biomedical research have been greatly facilitated by significant and sustained genomics technology throughput increases, cost decreases, and improvements in ease of use. The prop ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  10. PAR-18-303: Innovative Molecular Analysis Technology Development for Cancer Research and Clinical Care (R43/R44 Clinical Trial Not Allowed)

    Release Date: 10-03-2017Open Date: 03-05-2018 Due Dates: Multiple Close Date: 01-05-2021

    This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) proposing research for commercial development of novel cancer-relevant technologies. The proposed research projects are expected to focus on the development of highly-innovative technologies that improve molecular and/or cellular analysis of cancer ...

    SBIR Department of Health and Human ServicesNational Institutes of Health

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