Open Topic Search

Reset

NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

Displaying 1 - 10 of 469 results
  1. PAR-17-200 : Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R41)

    Release Date: 03-29-2017Open Date: 08-05-2017 Due Dates: Multiple Close Date: 01-05-2020

    Purpose The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and participating Institutes within the National Institutes of Health (NIH) encourage small business STTR grant applications to address different and complementary research needs for the development of appropriate pediatric drug formulations in different age groups. This FOA also encourages the deve ...

    STTR Department of Health and Human Services
  2. PAR-17-199 : Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R43)

    Release Date: 03-29-2017Open Date: 08-05-2017 Due Dates: Multiple Close Date: 01-05-2020

    Purpose The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and participating Institutes within the National Institutes of Health (NIH) encourage small business SBIR grant applications to address different and complementary research needs for the development appropriate pediatric drug formulations in different age groups. This FOA also encourages the develop ...

    SBIR Department of Health and Human Services
  3. PAR-17-275 : NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44)

    Release Date: 05-10-2017Open Date: 08-05-2017 Due Dates: Multiple Close Date: 01-05-2018

    Purpose To facilitate the cooperation and partnering of public and private funding organizations, universities, academic medical centers, research institutes, contract research organizations, biotechnology companies, and pharmaceutical companies in the advancement of interventions for stroke prevention, treatment, and rehabilitation, NINDS has formed the NIH Stroke Clinical Trials Research Network ...

    SBIR Department of Health and Human Services
  4. RFA-DA-18-007 : Nasal Delivery of CNS Therapeutics (R41/R42)

    Release Date: 04-25-2017Open Date: 07-24-2017Due Date: 08-23-2017Close Date: 08-23-2017

    Section I. Funding Opportunity Description    Less than 2% of small molecule pharmacotherapeutics effectively cross the blood brain barrier (BBB) . Larger molecules, such as peptides or antibodies, are virtually impenetrable. Direct routes of administration (e.g., epidural-, intracerebral- or intracerebral ventricular delivery) are invasive, costly and impractical for repeated dosing int ...

    STTR Department of Health and Human Services
  5. RFA-DA-18-006 : Nasal Delivery of CNS Therapeutics (R43/R44)

    Release Date: 04-25-2017Open Date: 07-24-2017Due Date: 08-23-2017Close Date: 08-23-2017

    Section I. Funding Opportunity Description  Less than 2% of small molecule pharmacotherapeutics effectively cross the blood brain barrier (BBB). Larger molecules, such as peptides or antibodies, are virtually impenetrable. Direct routes of administration (e.g., epidural-, intracerebral- or intracerebral ventricular delivery) are invasive, costly and impractical for repeated dosing into the CN ...

    SBIR Department of Health and Human Services
  6. RFA-DA-17-010 : Wearable to Track Recovery and Relapse Factors for People w/ Addiction (R43/R44)

    Release Date: 05-12-2017Open Date: 07-15-2017Due Date: 08-15-2017Close Date: 08-15-2017

    Background Currently there is no cost effective tool which enables researchers to study drug addiction relapse in real time. The standard remains to be urine analysis or self-report/surveys. Unfortunately, depending on the drug, urine analysis can only detect recent drug use in the previous 24 to 72 hours. Even in the best case scenario and based on lab assay results, the associated intervention r ...

    SBIR Department of Health and Human Services
  7. PAR-17-201 : Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44)

    Release Date: 03-09-2017Open Date: 07-09-2017 Due Dates: Multiple Close Date: 05-07-2020

    A. Overview Recent advances in neuroscience offer unprecedented opportunities to discover new treatments for nervous system disorders. However, before a new chemical entity can be tested in a clinical setting, it must undergo a process of chemical optimization to improve potency, selectivity, and drug-like properties, followed by pre-clinical safety testing to meet the standards set by the Food an ...

    SBIR Department of Health and Human Services
  8. RFA-ES-17-004 : SBIR E-learning for HAZMAT and Emergency Response (R43/R44)

    Release Date: 05-15-2017Open Date: 06-28-2017Due Date: 07-28-2017Close Date: 07-28-2017

    This SBIR FOA focuses on the development of e-learning training products that assist both students and instructors with a variety of delivery platforms. Note that all products must be directly related to the health and safety training of workers exposed to hazardous (HAZMAT) materials such as chemical, biological, or radiological substances. Occupations that encompass workers exposed to these haza ...

    SBIR Department of Health and Human Services
  9. RFA-AR-18-005 : Small Business Innovation Research on Rare Musculoskeletal, Rheumatic and Skin Diseases (SBIR) (R43)

    Release Date: 04-11-2017Open Date: 06-10-2017Due Date: 07-10-2017Close Date: 07-10-2017

    Purpose The purpose of this funding opportunity announcement (FOA) is to advance translational research for rare musculoskeletal, rheumatic or skin diseases by supporting preclinical projects conducted by small business concerns (SBCs) to develop biomarkers and/or therapies. The 2010 Institute of Medicine Report “Rare Diseases and Orphan Products: Accelerating Research and Development” (https: ...

    SBIR Department of Health and Human Services
  10. RFA-CA-17-024 : SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics Toward Commercialization (R44)

    Release Date: 04-12-2017Open Date: 06-06-2017Due Date: 07-06-2017Close Date: 07-06-2017

    Purpose The Small Business Innovation Research (SBIR) Program is an important mechanism by which the National Institutes of Health (NIH) and other Federal agencies help bring innovative solutions to public health challenges. A major objective of the Federal SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of medic ...

    SBIR Department of Health and Human Services

Agency Micro-sites

US Flag An Official Website of the United States Government