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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PAR-18-779: Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed)

    Release Date: 05-09-2018Open Date: 09-02-2018 Due Dates: Multiple Close Date: 01-07-2021

    This Funding Opportunity Announcement (FOA) seeks small business grant applications to develop major advances in genomic technologies. Advances in basic research, clinical applications of genomics and more broadly in biomedical research have been greatly facilitated by significant and sustained genomics technology throughput increases, cost decreases, and improvements in ease of use. The prop ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  2. PA-18-705 : SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)

    Release Date: 03-06-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    The SBIR Technology Transfer (SBIR-TT) Funding Opportunity Announcement (FOA) is intended to help move commercially-viable technologies from the NIH Intramural Program to the marketplace. Small Business Concerns (SBCs) are encouraged to submit applications that further develop available technologies from the NIH Intramural Program and bring them to the commercial market. While universities can spi ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  3. PA-18-708 : Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)

    Release Date: 03-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 09-05-2021

    Background G-protein coupled receptor proteins (GPCRs) are membrane bound proteins that serve to modulate cellular activities. Many of the GPCRs have potential significance in healthy mental function and in mental disorders, including receptors for most neurotransmitters and neuropeptides. Drugs targeting GPCRs are currently used in the treatment of mental disorders such as schizophrenia, anxie ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  4. PA-18-709: Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42 Clinical Trial Not Allowed)

    Release Date: 03-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 09-05-2021

    Background G-protein coupled receptor proteins (GPCRs) are membrane bound proteins that serve to modulate cellular activities. Many of the GPCRs have potential significance in healthy mental function and in mental disorders, including receptors for most neurotransmitters and neuropeptides. Drugs targeting GPCRs are currently used in the treatment of mental disorders such as schizophrenia, ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  5. PA-18-786 : Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)

    Release Date: 05-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  6. PA-18-785 : Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)

    Release Date: 05-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  7. RFA-CA-18-011: SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)

    Release Date: 02-14-2018Open Date: 07-15-2018Due Date: 08-15-2018Close Date: 08-15-2018

    Purpose The Small Business Innovation Research (SBIR) Program is an important mechanism by which the National Institutes of Health (NIH) and other Federal agencies help bring innovative solutions to public health challenges. A major objective of the Federal SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of me ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  8. RFA-HD-19-001 : Safe and Effective Devices for Use In Neonatal, Perinatal and Pediatric Care Settings (R43/R44 Clinical Trial Optional)

    Release Date: 03-05-2018Open Date: 07-01-2018Due Date: 08-01-2018Close Date: 08-01-2018

    Purpose            A major objective of this funding opportunity announcement (FOA) is to invite SBIR applications to foster collaboration between clinical and bioengineering research communities to develop and test safe, accurate, and effective devices for use in neonatal, perinatal, and pediatric care settings. These can be new devices or impr ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  9. RFA-ES-18-006 : SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)

    Release Date: 04-25-2018Open Date: 06-30-2018Due Date: 07-31-2018Close Date: 07-31-2018

    This SBIR FOA focuses on the development of e-Learning health and safety training products from a variety of delivery methods to assist both students and instructors in the training and education process. Note that all products must be directly related to the health and safety training of workers exposed to hazardous (HAZMAT) materials such as chemical, biological, or radiological substances, and ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  10. RFA-HL-19-018 : NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

    Release Date: 05-16-2018Open Date: 06-27-2018 Due Dates: Multiple Close Date: 07-09-2020

    Purpose The Small Business Innovation Research (SBIR) Program is an important National Institutes of Health (NIH) funding mechanism used to develop innovative solutions that address public health challenges. A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical products is ofte ...

    SBIR Department of Health and Human ServicesNational Institutes of Health

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