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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-AG-23-029: NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R43/R44 Clinical Trial Optional)

    Release Date: 07-06-2022Open Date: 01-17-2023Due Date: 02-17-2023Close Date: 02-18-2023

    The number of available tenure-track faculty positions has not kept pace with the growing number of Ph.D. graduates in recent years. This imbalance has created a highly competitive job environment, making it increasingly difficult for Ph.D. graduates to transition to academic appointments. Doctoral and post-doctoral training programs have heavily revolved around developing skill sets that are dire ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. RFA-AG-23-030: NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional)

    Release Date: 07-06-2022Open Date: 01-17-2023Due Date: 02-17-2023Close Date: 02-18-2023

    Background and Need The number of available tenure-track faculty positions has not kept pace with the growing number of Ph.D. graduates in recent years. This imbalance has created a highly competitive job environment, making it increasingly difficult for Ph.D. graduates to transition to academic appointments. Doctoral and post-doctoral training programs have heavily revolved around developing ski ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. DHS231-001: Accurate and Real-time Hardware-assisted Detection of Cyber Attacks

    Release Date: 11-17-2022Open Date: 12-15-2022Due Date: 01-17-2023Close Date: 01-17-2023

    Develop a hardware-assisted real-time accurate detector of cyber-attacks on networked and edge electronic devices. An increasing number of network-connected devices and systems in modern-day life are vulnerable to many attacks. Beyond the traditional computing systems and cloud services, modern Internet-of-Things (IoT) and cyber-physical systems can experience numerous cyber-attacks, such as rans ...

    SBIRPhase IDepartment of Homeland SecurityScience and Technology Directorate
  4. DHS231-002: Air Cargo Manifest Analysis to Aid Screeners

    Release Date: 11-17-2022Open Date: 12-15-2022Due Date: 01-17-2023Close Date: 01-17-2023

    Develop software to correlate items on a shipping manifest with images obtained from the screening of air cargo skids. Air cargo screening is performed by Transportation Security Administration (TSA) regulated entities. As private enterprises these entities need to screen air cargo for aviation security threats in an effective manner but also need to do so in economically viable ways. Screening a ...

    SBIRPhase IDepartment of Homeland SecurityScience and Technology Directorate
  5. DHS231-003: First Responder Digital Badges

    Release Date: 11-17-2022Open Date: 12-15-2022Due Date: 01-17-2023Close Date: 01-17-2023

    Develop an interoperable digital software badge capability that can securely and efficiently prove a first responder personnel’s identity and qualifications onsite in a disaster response operating environment. Many first responder organizations at various levels, inclusive of government, local and state, and non-profit agencies each have different methods on identifying first responders on scen ...

    SBIRPhase IDepartment of Homeland SecurityScience and Technology Directorate
  6. DHS231-004: Machine Learning Based Integration of Alarm Resolution Sensors

    Release Date: 11-17-2022Open Date: 12-15-2022Due Date: 01-17-2023Close Date: 01-17-2023

    Develop an integrated Alarm Resolution sensor suite with smart algorithms to enable high collection efficiency of explosive samples and signatures and enhance AR detectors’ performance, while simultaneously reducing user information overload. Explosive threats come in all shapes, sizes, concealments, and nuanced formulations. Due to these complexities, DHS Components employ a variety of detecto ...

    SBIRPhase IDepartment of Homeland SecurityScience and Technology Directorate
  7. DHS231-005: Mission Critical Services Server-to-Server Communication, voice communications, 3GPP-Standards

    Release Date: 11-17-2022Open Date: 12-15-2022Due Date: 01-17-2023Close Date: 01-17-2023

    Develop testing methods and processes to ensure conformance and interoperability of Mission Critical Services server-to-server communications. Mission critical services were implemented in the Third Generation Partnership Project (3GPP) standards to provide public safety users with highly resilient and high-performance network capabilities, such as quality of service, priority and preemption. Ce ...

    SBIRPhase IDepartment of Homeland SecurityScience and Technology Directorate
  8. DHS231-006: Reduced Order Modeling of Critical Infrastructure Protect Surfaces

    Release Date: 11-17-2022Open Date: 12-15-2022Due Date: 01-17-2023Close Date: 01-17-2023

    Develop a technique for generating reduced-order models of the protect surface of a cyber-physical-human critical infrastructure system enabling a comprehensive vulnerability assessment against catastrophic, model-based destabilization attacks. Today's critical infrastructures are complex, dynamic, cyber-physical-human systems. These systems often can hide intricate sensitivities to small per ...

    SBIRPhase IDepartment of Homeland SecurityScience and Technology Directorate
  9. DHS231-007: Theoretical Classification Methodologies to Enable Detection with Predicted Signatures

    Release Date: 11-17-2022Open Date: 12-15-2022Due Date: 01-17-2023Close Date: 01-17-2023

    Classification software that derives theoretically calculated signatures/spectra of unknown, not yet created, toxic compounds. The government seeks innovative methods to create theoretical spectroscopic signatures of potentially toxic chemical compounds for use in detection systems. Compounds of interest include chemical warfare agents (CWAs), toxic industrial compounds (TICs), pharmaceutical ba ...

    SBIRPhase IDepartment of Homeland SecurityCountering Weapons of Mass Destruction
  10. PAR-22-254: Limited Competition: IDeA Regional Entrepreneurship Development (I-RED) Program (STTR) (UT2 Clinical Trial Not Allowed)

    Release Date: 09-16-2022Open Date: 12-06-2022Due Date: 01-06-2023Close Date: 01-07-2023

    Background The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, also known as America’s seed fund, support US-owned and operated small businesses to engage in federal research and development that has a strong potential for commercialization. NIH’s SBIR and STTR programs invest over 1.2 billion dollars into health and life science companies tha ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
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