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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. NIH/NCI 370: Targeted Therapy for Cancer-and Cancer Therapy-Related Cachexia

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 2-3 Budget (total costs, per award): Phase I: up to $300,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Cachexia is characterized by a dramatic loss of skeletal muscle and adipose tissue mass, which cannot be r ...

    SBIR Department of Health and Human Services
  2. NIH/NCI 371: Drugs to Exploit the Immune Response Generated by Radiation Therapy

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 2-3 Budget (total costs, per award): Phase I: up to $300,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Tumor irradiation promotes recruitment of immune activating cells into the tumor microenvironment, including ...

    SBIR Department of Health and Human Services
  3. NIH/NCI 372: Development and Validation of Non-Mouse Reagents to Enable Preclinical Development of Novel Therapeutics

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 3-5 Budget (total costs, per award): Phase I: up to $300,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary The preclinical development of cancer therapeutics, including the recent trend and focus on cancer immunothe ...

    SBIR Department of Health and Human Services
  4. NIH/NCI 373: Tools and Technologies for Monitoring RNA Modifications

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will not be accepted. Number of anticipated awards: 3-5 Budget (total costs, per award): Phase I: up to $300,000 for up to 9 months Phase II: up to $1,500,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Chemical modifications play a crucial role in the regulation of biological processes. Protein function ...

    SBIR Department of Health and Human Services
  5. NIH/NCI 374: Novel Approaches for Local Delivery of Chemopreventive Agents

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted Number of anticipated awards: 3-5 Budget (total cost per award): Phase I: up to $300,000 for up to 9 months Phase II: up to 2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary The clinical value of an agent is reflected by both its efficacy and its toxicity. In the chemoprevention space, ...

    SBIR Department of Health and Human Services
  6. NIH/NCI 375: Diagnostic Imaging for Cancer Immunotherapies

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 3-4 Budget (total costs, per award): Phase I: up to $300,000 for up to 9 months Phase II: up to $2,200,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Immunotherapies have emerged as one of the promising approaches for cancer treatment by exploiting patients& ...

    SBIR Department of Health and Human Services
  7. NIH/NCI 376: Imaging-Based Tools for Longitudinal and Multi-Dimensional Mapping of the Tumor and its Microenvironment

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 3-5 Budget (total costs, per award): Phase I: up to $300,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Evolution of cancer is complex: from the early lesion to the development of primary tumor to widespread meta ...

    SBIR Department of Health and Human Services
  8. NIH/NCI 377: Bridging the Guideline Implementation Gap: Clinical Decision-Support to Improve Cancer Symptom Management

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 1-2 Budget (total costs, per award): Phase I: up to $225,000 for up to 9 months Phase II: up to $1,500,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Uncontrolled symptoms during and following cancer treatment have been associated with emotional distress; di ...

    SBIR Department of Health and Human Services
  9. NIH/NCI 378: Mobile Application for Surveillance of Post-Radiation Therapy Health-Related Quality of Life

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 3-4 Budget (total costs, per award): Phase I: up to $225,000 for up to 9 months Phase II: up to $1,500,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary The goal of this topic is to develop mobile applications for reporting toxicities after radiation therapy, e ...

    SBIR Department of Health and Human Services
  10. NIH/NCI 379: Software Enabling Data Integration from Wearable Sensors to Generate Novel Analytics for Cancer Patients

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 2-3 Budget (total costs, per award): Phase I: up to $225,000 for up to 9 months Phase II: up to $1,500,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary The rapid adoption of wearable and external sensing platforms since 2015, by the consumer health market, has ...

    SBIR Department of Health and Human Services

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