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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-ES-18-008 : Novel Approaches for Characterizing Exposure and Response to Engineered Nanomaterials (R43 Clinical Trials Not Allowed)

    Release Date: 07-03-2018Open Date: 08-11-2018Due Date: 09-11-2018Close Date: 09-11-2018

    Background Over the past decade the nanotechnology industry has expanded from a clean room technology to small scale industry generating thousands of ENMs now being used in everyday products ranging from personal care products to packaging, construction, water filtration, and children's clothes and toys. This widespread production and use of ENMs present opportunities for unintended human exp ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  2. PA-18-819 : Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44- Clinical Trial Optional)

    Release Date: 06-06-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 01-05-2021

    The NIH and other research sponsors invest a significant amount of funds in the development of new technologies to study the brain and behavior, from basic and clinical perspectives, through a variety of mechanisms, including, from NIH, the R01, R21, R33, P01, P41, and P50 grants. This investment has produced a large number of technologies that include hardware (e.g., instruments, devices, etc.), ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  3. PA-18-816 : Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42- Clinical Trial Not Allowed)

    Release Date: 06-05-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Fetal bovine serum (FBS) is the most widely used growth supplement for cell culture; it cost-effectively supports the survival, growth, and differentiation of many cell lines by providing nutrients, growth signals, and protection from stress. Although serum is an effective growth promoter, it is variable in its composition, activity, and effects on cellular phenotypes. This variability introduces ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  4. PA-18-815 : Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44- Clinical Trial Not Allowed)

    Release Date: 06-05-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Fetal bovine serum (FBS) is the most widely used growth supplement for cell culture; it cost-effectively supports the survival, growth, and differentiation of many cell lines by providing nutrients, growth signals, and protection from stress. Although serum is an effective growth promoter, it is variable in its composition, activity, and effects on cellular phenotypes. This variability introduces ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  5. PAR-18-801 : Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R43/R44- Clinical Trial Optional)

    Release Date: 05-24-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 01-05-2021

    Purpose This Funding Opportunity Announcement (FOA) encourages grant applications from SBCs to develop or adapt, apply, and validate existing or emerging technologies into user-friendly, low-resource setting-appropriate technologies for cancer prevention, diagnosis, or treatment. Projects proposed for this FOA will require multidisciplinary efforts to succeed, and, therefore, all app ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  6. PAR-18-802: Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42- Clinical Trial Optional)

    Release Date: 05-24-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 01-05-2021

    Purpose This Funding Opportunity Announcement (FOA) encourages grant applications from SBCs to develop or adapt, apply, and validate existing or emerging technologies into user-friendly, low-resource setting-appropriate technologies for cancer prevention, diagnosis, or treatment. Projects proposed for this FOA will require multidisciplinary efforts to succeed, and, therefore, all app ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  7. RFA-HL-19-018 : NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

    Release Date: 05-16-2018Open Date: 06-27-2018 Due Dates: Multiple Close Date: 07-09-2020

    Purpose The Small Business Innovation Research (SBIR) Program is an important National Institutes of Health (NIH) funding mechanism used to develop innovative solutions that address public health challenges. A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical products is ofte ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  8. RFA-HL-19-017 : NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

    Release Date: 05-16-2018Open Date: 06-27-2018 Due Dates: Multiple Close Date: 07-09-2020

    Purpose The Small Business Innovation Research (SBIR) Program is an important funding mechanism that the National Institutes of Health (NIH) uses to develop innovative solutions that address public health challenges. A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical product ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  9. PA-18-786 : Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)

    Release Date: 05-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  10. PA-18-785 : Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)

    Release Date: 05-15-2018Open Date: 08-05-2018 Due Dates: Multiple Close Date: 04-05-2021

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring ...

    STTR Department of Health and Human ServicesNational Institutes of Health

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