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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. 001: Novel Tools and Devices for Animal Research Facilities and to Support the Care of Animal Models (R43/R44)

    Release Date: 04-16-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 09-05-2018

    Many NIH-funded research projects rely on vertebrate and invertebrate animals to study fundamentals of biology and physiology, to investigate pathological conditions, to build models of human diseases, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the devel ...

    SBIR Department of Health and Human Services
  2. 001: Development of Novel Tools and Devices to Support the Care of Animal Models and Animal Care Research Facilities (R41/R42)

    Release Date: 04-16-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 09-05-2018

    Many NIH-funded research projects rely on vertebrate and invertebrate animals to study fundamentals of biology and physiology, to investigate pathological conditions, to build models of human diseases, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the devel ...

    STTR Department of Health and Human Services
  3. PA-15-336: Imaging Diagnostics of Dental Diseases and Conditions (Caries, Periodontal Disease, Cracked Teeth, and Pulp Vitality) (R41/R42)

    Release Date: 08-20-2015Open Date: 12-05-2015 Due Dates: Multiple Close Date: 09-07-2018

    The focus of this funding opportunity announcement (FOA) is to encourage the development of devices that will improve diagnosis of the following oral diseases and conditions: 1) caries after the appearance of white spot lesions and before penetration through the enamel-dentin junction; 2) severity and status of periodontal disease; 3) cracks in teeth and the depth of their extension into the tooth ...

    STTR Department of Health and Human Services
  4. PA-15-335 : Imaging Diagnostics of Dental Diseases and Conditions (Caries, Periodontal Disease, Cracked Teeth, and Pulp Vitality) (R43/R44)

    Release Date: 08-20-2015Open Date: 12-05-2015 Due Dates: Multiple Close Date: 09-07-2018

    The focus of this funding opportunity announcement (FOA) is to encourage the development of devices that will improve diagnosis of the following oral diseases and conditions: 1) caries after the appearance of white spot lesions and before penetration through the enamel-dentin junction; 2) severity and status of periodontal disease; 3) cracks in teeth and the depth of their extension into the tooth ...

    SBIR Department of Health and Human Services
  5. PA-15-354 : SBIR Technology Transfer (R43/R44)

    Release Date: 09-21-2015Open Date: 12-05-2015 Due Dates: Multiple Close Date: 09-05-2018

    The SBIR Technology Transfer (SBIR-TT) Funding Opportunity Announcement (FOA) is intended to help move commercially-viable technologies from the NIH Intramural Program to the marketplace. Small Business Concerns (SBCs) are encouraged to submit applications that further develop available technologies from the NIH Intramural Program and bring them to the commercial market. While universities can spi ...

    SBIR Department of Health and Human Services
  6. Small Business Alzheimer's Disease Research (R43/R44)

    Release Date: 02-01-2016Open Date: 03-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD.  As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of ...

    SBIR Department of Health and Human Services
  7. Small Business Alzheimer's Disease Research (R41/R42)

    Release Date: 02-01-2016Open Date: 03-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD.  As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of ...

    STTR Department of Health and Human Services
  8. PA-16-158 : New Technologies for the Glycosciences (R41/42)

    Release Date: 03-30-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

    STTR Department of Health and Human Services
  9. PA-16-157: New Technologies for the Glycosciences (R43/R44)

    Release Date: 03-30-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

    SBIR Department of Health and Human Services
  10. Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R43/R44)

    Release Date: 04-12-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Innovation Research (SBIR) grant applications from Small Business Concerns (SBCs) and academic partners that will focus on innovative technologies and strategies to improve HIV envelope protein expression, yield and rapid universal purification platforms that would meet the requirements of regulatory ...

    SBIR Department of Health and Human Services

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