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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. NIH/NIAID 055: Adjuvant Development for Vaccines and for Autoimmune and Allergic Diseases

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted Number of anticipated awards: 1-3 Budget (total costs): Phase I: $300,000/year for up to 2 years Phase II: $1,000,000/year for up to 3 years Background Adjuvants stimulate innate and/or adaptive immune responses. For the purpose of this SBIR, vaccine adjuvants are defined according to the U.S. Food and Drug Administration (FDA) as “agents added to, ...

    SBIR Department of Health and Human Services
  2. NIH/NIAID 054: Adjuvant Discovery for Vaccines and for Autoimmune and Allergic Diseases

    Release Date: 07-18-2017Open Date: 07-18-2017Due Date: 10-20-2017Close Date: 10-20-2017

    Fast-Track proposals will be accepted. Number of anticipated awards: 1-3 Budget (total costs): Phase I: $300,000/year for up to 2 years Phase II: $1,000,000/year for up to 3 years Background The goal of this program is to support the screening for new vaccine adjuvant candidates against infectious diseases or for toleragenic adjuvants for autoimmune or allergic diseases. Traditionally, adjuvan ...

    SBIR Department of Health and Human Services
  3. 2: ADVANCED DIGITAL NETWORK TECHNOLOGIES AND MIDDLEWARE SERVICES

    Release Date: 07-17-2017Open Date: 08-14-2017Due Date: 10-16-2017Close Date: 10-16-2017

    Please Note that a Letter of Intent is due Tuesday, September 05, 2017 PROGRAM AREA OVERVIEW: OFFICE OF ADVANCED SCIENTIFIC COMPUTING RESEARCH The primary mission of the Advanced Scientific Computing Research (ASCR) program is to discover, develop, and deploy computational and networking capabilities to analyze, model, simulate, and predict complex phenomena important to the Department of Energy ...

    SBIRSTTR Department of Energy
  4. 20: ADVANCED FOSSIL ENERGY SEPARATIONS AND ANALYSIS RESEARCH

    Release Date: 07-17-2017Open Date: 08-14-2017Due Date: 10-16-2017Close Date: 10-16-2017

    Please Note that a Letter of Intent is due Tuesday, September 05, 2017 PROGRAM AREA OVERVIEW: OFFICE OF BASIC ENERGY SCIENCES   Maximum Phase I Award Amount: $150,000 Maximum Phase II Award Amount: $1,000,000 Accepting SBIR Applications: YES Accepting STTR Applications: YES   For the foreseeable future, the energy ...

    SBIRSTTR Department of Energy
  5. 19: ADVANCED FOSSIL ENERGY TECHNOLOGY RESEARCH

    Release Date: 07-17-2017Open Date: 08-14-2017Due Date: 10-16-2017Close Date: 10-16-2017

    Please Note that a Letter of Intent is due Tuesday, September 05, 2017 PROGRAM AREA OVERVIEW: OFFICE OF BASIC ENERGY SCIENCES   Maximum Phase I Award Amount: $150,000 Maximum Phase II Award Amount: $1,000,000 Accepting SBIR Applications: YES Accepting STTR Applications: YES   For the foreseeable future, the energy ...

    SBIRSTTR Department of Energy
  6. 8: ADVANCED MAGNET DESIGN CODE FOR X-RAY AND NEUTRON FACILITIES

    Release Date: 07-17-2017Open Date: 08-14-2017Due Date: 10-16-2017Close Date: 10-16-2017

    Please Note that a Letter of Intent is due Tuesday, September 05, 2017PROGRAM AREA OVERVIEW: OFFICE OF BASIC ENERGY SCIENCESMaximum Phase I Award Amount: $150,000 Maximum Phase II Award Amount: $1,000,000 Accepting SBIR Applications: YES Accepting STTR Applications: YES  The Office of Basic Energy Sciences (BES), within the DOE’s Office of Science, is responsible for current and future user ...

    SBIRSTTR Department of Energy
  7. 10: ADVANCED TEMPERATURE AND ENVIRONMENTAL CONTROL FOR NEAR-FIELD OPTICAL MICROSCOPY AND NANOMETER-SCALE INFRARED SPECTROSCOPY

    Release Date: 07-17-2017Open Date: 08-14-2017Due Date: 10-16-2017Close Date: 10-16-2017

    Please Note that a Letter of Intent is due Tuesday, September 05, 2017 PROGRAM AREA OVERVIEW: OFFICE OF BASIC ENERGY SCIENCES Maximum Phase I Award Amount: $150,000 Maximum Phase II Award Amount: $1,000,000 Accepting SBIR Applications: YES Accepting STTR Applications: YES   The Department of Energy seeks to advance in o ...

    SBIRSTTR Department of Energy
  8. PAS-17-065: Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42)

    Release Date: 12-02-2016Open Date: 03-05-2017 Due Dates: Multiple Close Date: 09-05-2019

    In the United States (US), it is estimated that more than 5 million people suffer from Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD).  By 2050 this number is forecast to rise to more than 15 million.  Moreover, caring for and treating patients with AD/ADRD is expensive.  Current estimated annual costs for care and treatment of AD/ADRD total approximately ...

    STTR Department of Health and Human Services
  9. PAS-17-064 : Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44)

    Release Date: 12-02-2016Open Date: 03-05-2017 Due Dates: Multiple Close Date: 09-05-2019

    In the United States (US), it is estimated that more than 5 million people suffer from Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD).  By 2050 this number is forecast to rise to more than 15 million.  Moreover, caring for and treating patients with AD/ADRD is expensive.  Current estimated annual costs for AD/ADRD care and treatment total approximately $20 ...

    SBIR Department of Health and Human Services
  10. 8.4: Air, Water and Soils

    Release Date: 07-05-2017Open Date: 07-05-2017Due Date: 10-05-2017Close Date: 10-05-2017

    Contact Dr. Karelyn Cruz, National Program Leader for SBIR Air, Water and Soils at karelyn.cruz@nifa.usda.gov or (202) 604-7742 regarding questions about the topic area or to arrange a telephone consultation. Background The Air, Water and Soils topic area aims to develop and commercialize technologies and innovations for conserving, monitoring and protecting air, water and soil resources while sus ...

    SBIR Department of Agriculture

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