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Background The involvement of small businesses in translational aging research could hasten the pace at which scientific advances are transformed into commercial products to improve or maintain the health and functional independence of older adults. Therefore, this funding opportunity announcement (FOA) is intended to support innovative research conducted by small businesses to advance the availa ...

Background The involvement of small businesses in translational aging research could hasten the pace at which scientific advances are transformed into commercial products to improve or maintain the health and functional independence of older adults. Therefore, this funding opportunity announcement (FOA) is intended to support innovative research conducted by small businesses to advance the availa ...

Purpose This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to implement investigator-initiated clinical trials. A clinical trial is defined by NIH as: “A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo ...

Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD. As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of old ...

Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD. As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of old ...

Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Innovation Research (SBIR) grant applications from Small Business Concerns (SBCs) and academic partners that will focus on innovative technologies and strategies to improve HIV envelope protein expression, yield and rapid universal purification platforms that would meet the requirements of regulatory ...

Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Technology Transfer (STTR) grant applications from Small Business Concerns (SBCs) and non-profit research institutions that will focus on innovative technologies and strategies to improve HIV envelope protein expression, yield and rapid universal purification platforms that would meet the requirements ...

Research Objectives This FOA supports the development of health IT products to advance the “Zero Suicide” goal of preventing suicide attempts and deaths among individuals under care within health systems. A significant proportion of U.S. suicide decedents (more than 40,000 annually) have accessed health care within the year of their death, with estimates ranging from 30% to 80%, mirroring the ...