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Background An emerging area of scientific opportunity is the design and use of probes to study structure and function at the molecular and subcellular level in living cells. Approaches and tools such as labels that attach to specific peptide or nucleotide moieties, Fluorescent Resonance Energy Transfer, Green Fluorescent Protein (and mutant color variants), and genetically-engineered voltage or ...

Tools for germplasm cryopreservation have become increasingly important in enabling repositories to meet the needs for establishing banks of animal germplasm for current and future research needs. This funding opportunity announcement (FOA) solicits applications from SBCs for Small Business Technology Transfer (STTR) projects that propose innovative research in the areas of animal germplasm cryopr ...

Background Biomarkers are objective, measurable biochemical, genetic, or other biological indicators of a physiological or disease process. While some individual biomarkers are useful in biomedicine, complex conditions, such as mental illness, might benefit from constellations of several different biomarkers being used in concert. Whether used alone or in conjunction with others, biomarkers coul ...

Purpose The purpose of this funding opportunity is to reduce health disparities through the development and translation of appropriate medical technologies. The NIH defines health disparities as differences in the incidence, prevalence, morbidity, mortality, and burden of diseases and other adverse health outcomes that exist among specific population groups. These population groups are African ...

The SBIR program, as established by law, is intended to meet the following goals: stimulate technological innovation in the private sector; strengthen the role of small business in meeting Federal research or research and development (R/R&D) needs; increase the commercial application of Federally-supported research results; foster and encourage participation by socially and economically disadvanta ...

The STTR program, as established by law, is intended to stimulate a partnership of ideas and technologies between innovative small business concerns (SBCs) and non-profit research institutions through Federally-funded research or research and development (R/R&D). By providing awards to SBCs for cooperative R/R&D efforts with non-profit research institutions, the STTR program assists the small busi ...

Liver and biliary diseases affect Americans of all ages and all walks of life. Collectively liver and biliary diseases rank in the top 10 causes of mortality in the United States. Chronic liver diseases affect between 5 and 10 percent of Americans and account for 1 to 2 percent of deaths in the United States. Gallbladder disease affects an estimated 20 million Americans and causes considerable mor ...

Tools for germplasm cryopreservation have become increasingly important in enabling repositories to meet the needs for establishing banks of animal germplasm for current and future research needs. This funding opportunity announcement (FOA) solicits applications from SBCs for Small Business Innovation Research (SBIR) projects that propose innovative research in the areas of animal germplasm cryopr ...

For details, please refer to the solicitation details located at FedBizOpps website. In the event of a foreign animal disease (FAD) outbreak in the United States, such as highly pathogenic avian influenza or Foot and Mouth Disease (FMD), export markets will be severely impacted until the United States can regain international status as free from the disease. Freedom is achieved by containing th ...

For details, please refer to the solicitation details located at FedBizOpps website. In the current environment, our systems are built to operate in a relatively static configuration. For example, addresses, names, software stacks, networks, and various configuration parameters remain relatively static over relatively long periods of time. This static approach is a legacy of information technolo ...