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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

Displaying 17181 - 17190 of 19116 results
  1. : ES. Systems

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Systems' innovations combine multiple sub-elements and components together to enable the delivery of new value. Examples of previous systems innovations include the MP3 player, the artificial heart and the radio telescope.

    SBIRPhase INational Science Foundation
  2. : EC. Components

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Components represent basic building blocks for most engineered systems. By themselves, components are not typically consumed by end-users and they must be assembled together with other components to provide complete solutions. Examples of previous component innovations include: Micro-Electro-Mechanical Systems (MEMS)-based accelerometers, Sigma-Delta Analog to Digital Converters (ADC) and Optical ...

    SBIRPhase INational Science Foundation
  3. : ED. Devices

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Novel devices employ unique physical principles that enable broad advances in technology and industry. They often represent fundamental scientific and technological building blocks that require significant integration with other advanced technologies to provide commercial value. Examples of previous innovations in the device field include: the transistor, the thermocouple and Light Emitting Device ...

    SBIRPhase INational Science Foundation
  4. : Nanotechnology

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    The Nanotechnology subtopic addresses the creation and use of functional materials, devices, and systems with novel properties and functions that are achieved through the control of matter at a submicroscopic scale (from a fraction of nanometer to about 100 nm). Proposals should be market-driven and identify the end users of the proposed technology, and the proposed pathway to commercialization.

    SBIRPhase INational Science Foundation
  5. : Advanced Materials

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    The Advanced Materials subtopic addresses the research and development of new materials and systems that have the potential for revolutionary changes and paradigm shifts in U.S. industry. Proposals should be market-driven and identify the end users of the proposed technology, and the proposed pathway to commercialization.

    SBIRPhase INational Science Foundation
  6. : Manufacturing

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    The manufacturing subtopic addresses manufacturing innovations that improve the efficiency and competitiveness of the nation's manufacturing sector. Proposals should be market-driven and identify the end users of the proposed technology, and the proposed pathway to commercialization.

    SBIRPhase INational Science Foundation
  7. 313: RNAi Cancer Therapeutics using Nanotechnology

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    In 2011, the SBIR Development Center hosted an industry roundtable to solicit inputs from life science industry professionals on emerging areas that are ripe for technology development by the small business community. Participants at this meeting expressed strong interest in using the SBIR mechanism to foster and encourage the development of novel RNA interference (RNAi) delivery platforms, partic ...

    SBIRPhase IDepartment of Health and Human Services
  8. 314: Development of Human Tissue Culture Systems that Mimic the Tumor Microenvironment

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    There is a critical need to improve the accuracy of preclinical drug efficacy screening and testing through the development of in vitro culture systems that more effectively mimic the in vivo environment. Currently, two-dimensional (2D) in vitro culture systems or in vivo animal models are the primary tools used to test cancer cell responses to drugs. However, drug sensitivity data obtained via 2D ...

    SBIRPhase IDepartment of Health and Human Services
  9. 315: Development of Companion Diagnostics: Enabling Precision Medicine in Cancer Therapy

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    The demand for companion diagnostics has greatly increased with the recognition that matching the right patient to the right drug at the right time can improve patient care and may decrease health care costs. More than a dozen companion diagnostic tests have been approved by the FDA to guide the prescription of products in oncology, cardiovascular disease, and infectious disease. Among them, tests ...

    SBIRPhase IDepartment of Health and Human Services
  10. 316: Development of CTC Isolation Technologies Enabling Downstream Single Cell Molecular Analysis

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Summary Circulating tumor cells (CTCs) are cancer cells shed from either the primary tumor or its metastases and are circulating in the peripheral blood. While metastases are directly responsible for the majority of cancer deaths, CTCs may constitute seeds for metastases and may be instrumental for the spread of the disease. Many studies have shown that the presence of CTCs in peripheral blood or ...

    SBIRPhase IDepartment of Health and Human Services
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