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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

Displaying 17221 - 17230 of 18911 results
  1. 005: Reducing Antimicrobial Resistance through Improved use of Laboratory Testing Information in Healthcare Facilities

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: The reduction and eventual elimination of healthcare-associated infections (HAIs) and the combatting of antibiotic resistance in the pathogens causing these infections are national public health priorities as demonstrated in Department of Health and Human Services (HHS) national action plans. Public reporting of HAIs by hospitals using the National Healthcare Safety Network (NHSN) is m ...

    SBIRPhase IDepartment of Health and Human Services
  2. 034: Development of Biomedical Devices to Elicit Durable Protective Immunity against HIV

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: Substantial progress has been made recently towards identifying effective HIV prevention strategies. The RV144 trial demonstrated that an HIV vaccine comprised of a recombinant ALVAC prime + gp120 boost regimen was partially efficacious (VE=31.2%), although it’s protective effects waned over the study period and study volunteers faced barriers related to transportation to clinic for ...

    SBIRPhase IDepartment of Health and Human Services
  3. 035: Development of a Portable Multiplex Assay for Determination of Recent HIV-1 Infection

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: The estimation of HIV incidence, or the rate of new infections in a population, is an important public health indicator that provides valuable information on the growth of the epidemic and the efficacy of various intervention strategies. Within the past 15 years, a new strategy for estimating HIV incidence has been employed based on the observation that certain biomarkers (mainly HIV-s ...

    SBIRPhase IDepartment of Health and Human Services
  4. 036: Testing the Efficacy of Combination HIV Prevention Strategies in Nonhuman Primates

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: Although substantial progress has been made to identify new biomedical HIV prevention strategies, including topical and oral antiretroviral drug pre-exposure prophylaxis (PrEP) regimens and vaccines, they are not yet approved for general use. However, these preventions (or related derivatives) are likely to be implemented widely in upcoming years. The identification of HIV preventions ...

    SBIRPhase IDepartment of Health and Human Services
  5. 025: Development of an Inactivated Rotavirus Vaccine for Use in Global Immunization

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: The currently licensed oral rotavirus vaccines Rotarix™ and Rotateq™ are effective in reducing cases of severe diarrhea among children in high and middle income countries, but are significantly less effective in low income countries. In addition, both vaccines are associated with a low risk of diarrhea and intussusception among infants who receive the first dose of vaccine. To impr ...

    SBIRPhase IDepartment of Health and Human Services
  6. 026: Thermostable Dry Measles Vaccine Formulation for Sublingual Administration

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: Vaccines are one of the most powerful tools available for preventing disease. Measles vaccine has led to the elimination of endemic measles from the Western Hemisphere and a tremendous reduction in global mortality. However, the logistic difficulties inherent in vaccination by injection create barriers to high measles vaccine coverage. Vaccination by injection requires highly skilled v ...

    SBIRPhase IDepartment of Health and Human Services
  7. 002: Improved Methods for Collection, Preservation, and Transportation of Biological Specimens

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: CDC has both domestic and international laboratory programs that provide clinical specimen testing for the detection of known and emerging infections, chemical, or radiological agents that pose global health threats. Current methods for collection, storage, and transport of biological specimens are expensive and labor and material intensive. Clinical specimens are often collected by hi ...

    SBIRPhase IDepartment of Health and Human Services
  8. : Biological and Chemical Technologies (BC)

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    The Biological and Chemical Technologies (BC) topic addresses innovation in the life sciences and chemical areas including Biological Technologies, Biomedical Technologies, Environmental Technologies, and Chemical Technologies. Biological Technologies includes the subtopic areas of research tools, bioinstrumentation, biosensors, computational biology and bioinformatics, synthetic biology and metab ...

    SBIRPhase INational Science Foundation
  9. : Education Applications (EA)

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    The Education Application (EA) topic addresses the challenges of advancing STEM (science, technology, engineering, and mathematics) education for all American students, to nurture innovation, and to ensure the long-term economic prosperity of the Nation. The urgency of this task is underscored by the need to ensure that the United States continues to excel in science, technology, and innovation in ...

    SBIRPhase INational Science Foundation
  10. : Electronics, Information and Communication Technologies (EI)

    Release Date: 08-30-2012Open Date: 11-03-2012Due Date: 12-03-2012Close Date: 12-03-2012

    The NSF SBIR Program conceptualizes Electronics, Information and Communication Technologies in the form of a five-layer stack. Each layer of the stack builds upon the layer(s) below and supports the layer(s) above. At the foundation of this stack are devices. Devices (ED) are the building blocks for Components (EC) that are assembled into Systems (ES) built for Applications (IA) that are employed ...

    SBIRPhase INational Science Foundation
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