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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

Displaying 17221 - 17230 of 19116 results
  1. 150: Video Game Targeting Relapse Prevention in Youth with Substance Use Disorders

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Objective This topic addresses the need for improved relapse rates among adolescent substance abusers. A video game should be designed for substance using adolescents in a commercializable and compelling package, for the purpose of reinforcing and maintaining behavior changes (e.g., skills development) accomplished through a theory-driven and evidence-based therapy. The video game may be compatibl ...

    SBIRPhase IDepartment of Health and Human Services
  2. 003: Diagnostic Needs for Neglected Tropical Diseases (NTD) Programs

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: Neglected tropical diseases (NTDs) are bacterial and parasitic infections that disproportionately affect poor and marginalized populations around the world. A subset of NTDs, including lymphatic filariasis, onchocerciasis, schistosomiasis, trachoma and intestinal helminth infections, can be targeted effectively through mass chemotherapy. These NTDs are not considered to cause appreciab ...

    SBIRPhase IDepartment of Health and Human Services
  3. 004: Rapid Screening Tests to Prevent Congenital Infections and Ensure Blood Safety

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: During the past decade, several companies have developed lateral flow immunochromatographic devices to detect antibodies to individual communicable diseases. More recently, these platforms have also been adapted to detect specific antigens associated with these infections. These inexpensive point-of-care (POC) tests offer considerable advantages over conventional laboratory tests, sinc ...

    SBIRPhase IDepartment of Health and Human Services
  4. 005: Development of Diagnostic Tests for Strongyloidiasis and Schistosomiasis

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    putting international travelers at risk for infections with these organisms. In a 10-year period from 1997 to 2008, over 400 cases of schistosomiasis were reported in travelers to the international travelers’ health surveillance network (GeoSentinel). In addition, the United States resettles 50,000-80,000 refugees annually from around the world. It is estimated that the prevalence rates of paras ...

    SBIRPhase IDepartment of Health and Human Services
  5. 016: Improving Data, Improving Care, Making it Count

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: The number of people affected by complex childhood rare conditions (CCRC), such as spina bifida (SB), is estimated to be 1/1500 globally. While the prevalence of these conditions is low, they have high impact in terms of health care costs and impact on the family and the community. Reliable and valid clinical data are scarce and insufficient to identify and evaluate clinical practices ...

    SBIRPhase IDepartment of Health and Human Services
  6. 017: Smartphone Application for Global Birth Defects Surveillance

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: Every year approximately 8 million children are born worldwide with severe birth defects. Currently, data about the magnitude of birth defects prevalence in low and middle income countries are either nonexistent or severely underestimated, creating difficulties for health strategic planners to convince policy makers of the burden and the public health impact of birth defects in their c ...

    SBIRPhase IDepartment of Health and Human Services
  7. 033: A Mobile Phone Application (“App”) for Advancing Teen Pregnancy Prevention

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: The teen birth rate in the US remains high, particularly among racial/ethnic minorities compared with many other industrialized nations. The adverse consequences of teen pregnancy are substantial at individual, family, and community levels. A range of innovative tools and interventions is needed to foster an environment that enables teens to experience better reproductive health. In 20 ...

    SBIRPhase IDepartment of Health and Human Services
  8. 003: Development of Nanoparticle Dengue Diagnostic Tests

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: Dengue is a major public health problem in global tropical and subtropical areas. Primary prevention of this mosquito vector-borne (transmitted) disease is limited because vaccines are only in the late-stage development phase and vector control has been thus far unsuccessful. Dengue presents as an acute febrile illness often without signs or symptoms that differentiate it from other co ...

    SBIRPhase IDepartment of Health and Human Services
  9. 004: Development of Tests in a Standardized Kit Format for Diagnosis of Arboviral Infections in Resource-Limited, Primary Health Care Setting

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: Arthropod-borne virus infections may present with clinical symptoms similar to those of other bacterial or viral infections, such as a flu-like illness, encephalitis, or polio-like myelitis. Laboratory diagnosis is essential to determine etiology and calculate disease burden in order to guide treatment and control strategies, particularly if there is an effective vaccine available, suc ...

    SBIRPhase IDepartment of Health and Human Services
  10. 005: Reducing Antimicrobial Resistance through Improved use of Laboratory Testing Information in Healthcare Facilities

    Release Date: 08-15-2012Open Date: 08-15-2012Due Date: 12-03-2012Close Date: 12-03-2012

    Background: The reduction and eventual elimination of healthcare-associated infections (HAIs) and the combatting of antibiotic resistance in the pathogens causing these infections are national public health priorities as demonstrated in Department of Health and Human Services (HHS) national action plans. Public reporting of HAIs by hospitals using the National Healthcare Safety Network (NHSN) is m ...

    SBIRPhase IDepartment of Health and Human Services
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