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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

Displaying 18081 - 18090 of 19124 results
  1. OSD11-T03: Design and Analysis of Multi-core Software

    Release Date: 07-28-2011Open Date: 08-29-2011Due Date: 09-28-2011Close Date: 09-28-2011

    TECHNOLOGY AREAS: Information Systems OBJECTIVE: Develop innovative technologies for early design and analysis of multi-threaded software for multi-core systems enabling robust development of distributed, real-time systems targeted for dynamic environments. DESCRIPTION: The multi-core era has significantly impacted the way software is developed. While multi-core processors are expected to in ...

    STTRPhase IDepartment of DefenseOffice of the Secretary of Defense
  2. OSD11-T04: Operating System Mechanisms for Many-Core Systems

    Release Date: 07-28-2011Open Date: 08-29-2011Due Date: 09-28-2011Close Date: 09-28-2011

    TECHNOLOGY AREAS: Information Systems OBJECTIVE: Design and develop innovative technologies for operating system services that take advantage of abstract concepts to efficiently partition, communicate, and execute programs on many-core, multi-processor systems. DESCRIPTION: The Department of Defense (DoD) is heavily reliant on computational power to perform rapid analysis of sensor data, sea ...

    STTRPhase IDepartment of DefenseOffice of the Secretary of Defense
  3. OSD11-TD1: Information Salience

    Release Date: 07-28-2011Open Date: 08-29-2011Due Date: 09-28-2011Close Date: 09-28-2011

    TECHNOLOGY AREAS: Information Systems OBJECTIVE: Identify and understand methods for determining information value as a basis for future decision support systems. Devise mathematical, information science, and computer science representations of information salience to provide basis for automation and subsequent development of generalized information salience models and subsequent development o ...

    STTRPhase IDepartment of DefenseOffice of the Secretary of Defense
  4. 1: NATIONAL CANCER INSTITUTE (NCI)

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    The NCI is the Federal Government’s principal agency established to conduct and support cancer research, training, health information dissemination, and other related programs. As the effector of the National Cancer Program, the NCI supports a comprehensive approach to the problems of cancer through intensive investigation in the cause, diagnosis, prevention, early detection, treatment, ...

    SBIRPhase IDepartment of Health and Human Services
  5. 255 : Development of Anticancer Agents

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    The short term goal of this SBIR contract topic is to support small businesses that are developing novel candidate therapeutic agents of interest. The scope of work may include structure activity relationships (SAR), medicinal chemistry and formulation, animal efficacy testing, pharmacokinetic, pharmacodynamic, and toxicological studies, as well as production of GMP bulk drug and clinical ...

    SBIRPhase IDepartment of Health and Human Services
  6. 277: Development of Companion Diagnostic

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Recently, the demand for companion diagnostics has greatly increased with the recognition that matching the right patient to the right drug can improve patient care and may decrease health care costs. More than a dozen companion diagnostic tests have been approved by the FDA to guide the prescription of products in oncology, cardiovascular disease, and infectious disease. Among them, tests of Phil ...

    SBIRPhase IDepartment of Health and Human Services
  7. 291: Development of Radiation Modulators For Use During Radiotherapy

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Radiotherapy is employed in the treatment of over half of all cancer patients. Many of those patients however, may suffer some adverse effects from this therapy during and/or after treatment. In addition, in approximately half of the patients treated with curative intent, the tumors recur. Enhancing specific tumor killing and minimizing normal tissue damage from radiotherapy would improve tumor co ...

    SBIRPhase IDepartment of Health and Human Services
  8. 300: Reformulation of Cancer Therapeutics using Nanotechnology

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    The design of novel therapies and drug delivery systems for cancer is being enabled by nanotechnology. Nanoscale devices carrying therapeutic payloads and delivered within close proximity of the tumor in vivo will play a significant role in increasing the effectiveness of the treatment while decreasing severity of side effects. Such techniques would be highly relevant, particularly for organs that ...

    SBIRPhase IDepartment of Health and Human Services
  9. 301: Probing Tumor Microenvironment Using In Vivo Nanotechnology-based Sensors

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Biological fluids and tissue biopsies provide important information with respect to a diagnosis of cancer and to efficacy of its treatment. The collection of both (especially the biopsy) is invasive and can be achieved only in single time points with limited frequency. The analysis of biological fluids (blood, urine), which are easier to collect, do not provide for direct representation of the tum ...

    SBIRPhase IDepartment of Health and Human Services
  10. 306: Development of Innovative Algorithms for Processing & Analysis of In Vivo Images

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Image processing algorithms are increasingly important as imaging and image-guided intervention technologies become critical in screening, diagnosis, staging, treatment and monitoring of cancer patients. The use of in vivo imaging modalities such as MRI, X-ray, CT, Positron Emission Tomography, Nuclear Medicine, Ultrasound, Optical Coherence Tomography, and Photo-acoustic imaging, as well as multi ...

    SBIRPhase IDepartment of Health and Human Services
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