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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

Displaying 18141 - 18150 of 18924 results
  1. 070: Bioabsorbable Stents for Pediatric Pulmonary Artery Stenosis and Aortic Coarctation

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Mechanical stents to relieve obstructive cardiovascular lesions could have great utility in pediatric cardiology, but are unsuitable for small children. Commercially available stents limit vessel growth and require future surgical removal. Absorbable stents might revolutionize the treatment of congenital heart disease in children. Small children require small delivery systems for devices that are ...

    SBIRPhase IDepartment of Health and Human Services
  2. 071: Electrophysiologic Catheters for Interventional MRI Ablation of Ventricular Tachycardia

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Catheter-based ablation therapy is used to treat cardiac rhythm disorders. MRI may have value in targeting and assessing ablation lesions interactively during catheter based cardiac electrophysiology (EP) procedures. Real-time MRI EP ablation may be especially attractive to ablate mid-myocardial targets causing ventricular tachycardia in adults and children. While technically feasible, there are ...

    SBIRPhase IDepartment of Health and Human Services
  3. 4: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (NIAAA)

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    The NIAAA supports research on the causes, prevention, control, and treatment of the major health problems of alcohol abuse, alcoholism, and alcohol-related disorders. Through its extramural research programs, the NIAAA funds a wide range of basic and applied research to develop new and/or improved technologies and approaches for increasing the effectiveness of diagnosis, treatment, and prevention ...

    SBIRPhase IDepartment of Health and Human Services
  4. 044: Development of Novel Compounds to Treat Alcohol Use Disorders

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Efforts to develop medications for alcohol use disorders have expanded rapidly in recent years. Developing novel compounds for alcohol treatment is high priority for NIAAA Medications Development Program. Three agents directed at the addictive behavior in the use of alcohol —disulfiram, naltrexone, and acamprosate—are now approved for use in the United States and many other countries. Recently ...

    SBIRPhase IDepartment of Health and Human Services
  5. 5: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK)

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    The NIDDK supports research in diabetes, endocrinology and metabolic diseases; digestive diseases and nutrition; and kidney, urologic and hematologic diseases. For additional information about areas of interest to the NIDDK, please visit our home page at http://www.niddk.nih.gov.

    SBIRPhase IDepartment of Health and Human Services
  6. 075: A Low Molecular Weight Thyroid-Stimulating Hormone Receptor Agonist for Thyroid Cancer (NIH TT)

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    NIDDK investigators have discovered and are evaluating the first potent and efficacious small molecule agonist of the thyroid-stimulating hormone (TSH, thyrotropin) receptor (TSHR) that has potential for clinical application in patients with thyroid cancer. This agonist drug is intended for use in patients for 2-5 days at a time following thyroidectomy and at subsequent intervals after initial tre ...

    SBIRPhase IDepartment of Health and Human Services
  7. 6: NATIONAL INSTITUTE ON DRUG ABUSE (NIDA)

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    NIDA’s mission is to lead the nation in bringing the power of science to bear on drug abuse and addiction, through support and conduct of research across a broad range of disciplines and by ensuring rapid and effective dissemination and use of research results to improve prevention, treatment, and policy.

    SBIRPhase IDepartment of Health and Human Services
  8. 139: Confirming Compliance with Experimental Pharmacotherapy Treatment of Drug Abuse

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    It is strongly suggested that proposals adhere to the above budget amounts and project periods. Proposals with budgets exceeding the above amounts and project periods may not be funded. Assessing the results of clinical investigations of pharmacotherapies for treating drug abuse is made difficult by the lack of certainty that patients have taken the prescribed treatment as instructed. Negative o ...

    SBIRPhase IDepartment of Health and Human Services
  9. 140: Development of a Solid Oral Dosage Form for Fenobam

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    Addiction to cocaine is a serious health problem in the U.S. (currently estimated by the U.S. Office of National Drug Control Policy at 3 million individuals). Untreated cocaine dependence significantly increases health, social service, and criminal justice costs to society and is a major vector contributing to the spread of infectious diseases such as HIV, TB, and hepatitis. To date, there is no ...

    SBIRPhase IDepartment of Health and Human Services
  10. 141: Recovery Warrior: Behavioral Activation Video Game for Substance Abuse via a Commercially Available Active & Interactive Gaming Platform (e.g., Wii, Play Station Move, or Xbox Kinect)

    Release Date: 08-25-2011Open Date: 08-25-2011Due Date: 11-07-2011Close Date: 11-07-2011

    It is strongly suggested that proposals adhere to the above budget amounts and project periods. Proposals with budgets exceeding the above amounts and project periods may not be funded. Objective: This topic addresses the need for addiction treatment improvement by further developing and expanding an evidence-based therapy for use with in-treatment addicted populations through development of a c ...

    SBIRPhase IDepartment of Health and Human Services
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