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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

Displaying 18881 - 18890 of 19124 results
  1. 10: Research Tools

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    The NIAAA supports the development of new or improved tools to enhance the ability to conduct alcohol-related laboratory studies on humans and animals and to more effectively analyze data from large databases. Examples include transgenic animal models, cell lines, new ligands for neuroimaging, and simulators of alcohol impairment. Areas that may be of interest to small businesses i ...

    SBIRPhase IDepartment of Health and Human Services
  2. 11: Development of Biomolecular Signatures of Alcohol Exposure and Alcohol-induced Tissue Injury

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    Acute and chronic alcohol consumption leads to health-related complications and ultimately to significant societal costs. Quantitative and qualitative markers of high-risk drinking behavior and alcohol-induced tissue damage would greatly improve medical efforts to recognize and treat alcohol-related disorders. Traditional biomarkers currently in clinical use lack specificity, sensi ...

    SBIRPhase IDepartment of Health and Human Services
  3. 12: Clinical Testing of Biochemical Markers

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    The development of effective biochemical markers represents a powerful means for early diagnosis and treatment of alcohol dependent/abuse patients and for the identification of individuals who have a predisposition for alcoholism. There are two different types of biochemical markers: trait markers and state markers. Trait biomarkers have the ability to d ...

    SBIRPhase IDepartment of Health and Human Services
  4. 13: Stem Cell Research for Alcohol-induced Disorders

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    Stem cells are master cells in the body and they have the remarkable potential to develop into many different cell types. Stem cells may become a renewable source of replacement cells to treat alcohol related diseases. They can also be used to study disease processes, and to develop new and more effective drugs. Recent research progress on stem cells has ...

    SBIRPhase IDepartment of Health and Human Services
  5. 14: Real-time Detection of Neurochemical Changes in Response to Alcohol Drinking

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    Many pharmacological mechanisms of ethanol action in the brain are mediated by time-dependent neurochemical events in multiple brain regions. Despite great progress in identifying ethanol’s neurochemical actions, we do not fully know how neurochemicals change in real time following ethanol administration and drinking (acute and chronic). Multidimensional measurement of neurochemi ...

    SBIRPhase IDepartment of Health and Human Services
  6. 9: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS (NIDCD)

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    The NIDCD supports research on the normal mechanisms of, as well as on diseases and disorders of hearing, balance, smell, taste, voice, speech and language. The Institute also supports research related to disease prevention and health promotion. The NIDCD addresses special biomedical and behavioral problems associated with people who have communication impairments or disorders. The ...

    SBIRPhase IDepartment of Health and Human Services
  7. 1: Hearing and Balance Program

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    Research and development related to lost auditory function. Development of treatment modalities to prevent or lessen the effects of hearing disorders; development of new hearing aids, cochlear implants, and other assistive devices; development of systems designed to increase utilization of computers, telecommunication devices, or alerting systems by individuals with hearing impairm ...

    SBIRPhase IDepartment of Health and Human Services
  8. 2: Voice, Speech, and Language Programs

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    Research on voice, speech, and language disorders focuses on determining the nature, causes, treatment and prevention of communication disorders such as stuttering, spasmodic dysphonia, dysarthria, and aphasia. Emphasis is on research and development of diagnostic measures and intervention strategies for voice, speech, swallowing, and language disorders; development of communicatio ...

    SBIRPhase IDepartment of Health and Human Services
  9. 3: Taste and Smell Program

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    Research on the development of easily administered diagnostic tools for testing human chemosensory function in population studies; epidemiological studies of the prevalence of taste and smell disorders; intervention strategies for smell and taste disorders; development of bitter taste-blockers targeted toward pharmaceuticals; the development of artificial sweeteners; influence of t ...

    SBIRPhase IDepartment of Health and Human Services
  10. 8: NATIONAL INSTITUTE ON DRUG ABUSE (NIDA)

    Release Date: 01-24-2011Open Date: 03-05-2011Due Date: 01-08-2012Close Date: 01-08-2012

    The mission of the NlDA is to lead the nation in bringing the power of science to bear on drug abuse and addiction, through support and conduct of research across a broad range of disciplines and by ensuring rapid and effective dissemination and use of research results to improve prevention, treatment, and policy. For additional information about areas of interest to the NIDA, please visit ...

    SBIRPhase IDepartment of Health and Human Services
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