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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

Displaying 1 - 10 of 18910 results
  1. 1: Scope of the Program:

    Release Date: 08-12-2008Open Date: 11-05-2008Due Date: 09-08-2011Close Date: 09-08-2011

    The NINDS Translational Research Program is specifically focused on pre-clinical therapy development necessary to begin clinical testing of therapeutic candidates for neurological disorders. This program supports the pre-clinical development of drugs, biologics, and devices including activities from the identification of a therapeutic lead to Investigational New Drug (IND) or Investigational Devic ...

    SBIRPhase IDepartment of Health and Human Services
  2. 2: Phase I Awards (available only as part of a Fast-Track application):

    Release Date: 08-12-2008Open Date: 11-05-2008Due Date: 09-08-2011Close Date: 09-08-2011

    The scope of the Phase I portion of a Fast-Track in the program includes all activities in the pre-clinical therapy development pipeline, and the Phase I can be structured in any way necessary to support subsequent pre-clinical development tasks during the Phase II project. However, the Phase II awards in the program support milestone-driven projects that begin with identified candidate therapeuti ...

    SBIRPhase IDepartment of Health and Human Services
  3. 3: Phase II Awards

    Release Date: 08-12-2008Open Date: 11-05-2008Due Date: 09-08-2011Close Date: 09-08-2011

    The scope of a Phase II award in the program is the same whether it is based on a previously successful Phase I in the regular SBIR program or if it is part of a Fast-Track application. For entry to the program, projects must have one or more identified therapeutic leads and convincing proof-of-principle on efficacy demonstrated in credible models of the disease or against defined disease targets ...

    SBIRPhase IDepartment of Health and Human Services
  4. 4: Implementation

    Release Date: 08-12-2008Open Date: 11-05-2008Due Date: 09-08-2011Close Date: 09-08-2011

    The NINDS Cooperative Program in Translational Research Small Business Awards provides funding through the U44 cooperative agreements mechanism. As a cooperative agreement, implementation will involve participation of NINDS program staff in the planning and execution of these therapy-directed projects. The U44 cooperative agreements support translational research projects that are focused on a sin ...

    SBIRPhase IDepartment of Health and Human Services
  5. : Development of Biomarkers for Mental Health Research and Clinical Use

    Release Date: 12-12-2008Open Date: 03-05-2009Due Date: 01-08-2012Close Date: 01-08-2012

    Background Biomarkers are objective, measurable biochemical, genetic, or other biological indicators of a physiological or disease process. While some individual biomarkers are useful in biomedicine, complex conditions, such as mental illness, might benefit from constellations of several different biomarkers being used in concert. Whether used alone or in conjunction with others, biomarkers coul ...

    SBIRPhase IDepartment of Health and Human Services
  6. : Tools for Germplasm Cryopreservation

    Release Date: 12-18-2008Open Date: 03-05-2009Due Date: 01-08-2012Close Date: 01-08-2012

    Tools for germplasm cryopreservation have become increasingly important in enabling repositories to meet the needs for establishing banks of animal germplasm for current and future research needs. This funding opportunity announcement (FOA) solicits applications from SBCs for Small Business Technology Transfer (STTR) projects that propose innovative research in the areas of animal germplasm cryopr ...

    STTRPhase IDepartment of Health and Human Services
  7. 1: Tools for Germplasm Cryopreservation

    Release Date: 12-18-2008Open Date: 03-05-2009Due Date: 01-08-2012Close Date: 01-08-2012

    Tools for germplasm cryopreservation have become increasingly important in enabling repositories to meet the needs for establishing banks of animal germplasm for current and future research needs. This funding opportunity announcement (FOA) solicits applications from SBCs for Small Business Innovation Research (SBIR) projects that propose innovative research in the areas of animal germplasm cryopr ...

    SBIRPhase IDepartment of Health and Human Services
  8. : Probes for Microimaging The Nervous System

    Release Date: 12-19-2008Open Date: 03-05-2009Due Date: 01-08-2012Close Date: 01-08-2012

    Background An emerging area of scientific opportunity is the design and use of probes to study structure and function at the molecular and subcellular level in living cells. Approaches and tools such as labels that attach to specific peptide or nucleotide moieties, Fluorescent Resonance Energy Transfer, Green Fluorescent Protein (and mutant color variants), and genetically-engineered voltage or ...

    SBIRPhase IDepartment of Health and Human Services
  9. : Radiological/Nuclear Medical Countermeasure Product Development Program

    Release Date: 02-09-2009Open Date: 03-05-2009Due Date: 01-08-2012Close Date: 01-08-2012

    Purpose The purpose of this funding opportunity is to solicit Small Business Innovation Research (SBIR) grant applications (Phase I [R43] and Phase II [R44, both new and renewal applications]) that are focused on specific Investigational New Drug/Investigational Device Exemption (IND/IDE) enabling product development activities for radiological/nuclear medical countermeasures leading to IND or ...

    SBIRPhase IDepartment of Health and Human Services
  10. : New Technologies for Liver Disease

    Release Date: 02-11-2009Open Date: 03-05-2009Due Date: 01-08-2012Close Date: 01-08-2012

    Background Liver and biliary diseases affect Americans of all ages and all walks of life. Collectively liver and biliary diseases rank in the top 10 causes of mortality in the United States. Chronic liver diseases affect between 5 and 10 percent of Americans and account for 1 to 2 percent of deaths in the United States. Gallbladder disease affects an estimated 20 million Americans and causes con ...

    SBIRPhase IDepartment of Health and Human Services
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