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HHS SBIR PA-14-219
NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should use the agency link listed below which will take you directly to the appropriate agency server where you can read the official version of this solicitation and download the appropriate forms and rules.
The official link for this solicitation is: http://grants.nih.gov/grants/guide/pa-files/PA-14-219.html
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There are important technologies within the biomedical and biobehavioral space that do not require federal regulatory approvals as part of the technology development efforts, but that still require extraordinary time and effort to develop. The purpose of this FOA is to encourage applications for renewals of existing Phase II grants which are supporting research and development of such technologies.
Technologies encouraged by this FOA fall into three broad categories, which are described, below:
- Complex instrumentation: This is instrumentation comprising several distinct parts that must work together. Very often the goal of such projects is to deliver turnkey products for researchers. For example, high density electroencephalography instrumentation includes electrode arrays, amplifiers, data analytic and data visualization software, etc. Another example is non-invasive near infrared imaging instrumentation, which might include photon sources and detectors, timing devices for delivering photons, amplifiers, and software. Some high throughput assay systems may fall into this category.
- Clinical research tools: Such tools would include those that are developed for clinical research use that do not require any federal regulatory approval, but still require extensive development in order to demonstrate validity in a diverse population. For example, state of the art computerized patient assessment tools for mental disorders that are sensitive to developmental change, gender and cultural diversity, variation in cognitive and behavioral functioning and speech impairment. These tools may include data from blood work, medical history, objective biobehavioral information, and functional capacity.
- Behavioral interventions/treatments: Evidence-based behavioral interventions can play a role in the treatment of behavioral disorders. Novel means of providing these types of therapies (e.g., smart phone-based programs) require not only their development, and small efficacy studies, but also extensive, large scale testing to determine the treatments true effectiveness across diverse patient populations.
It is important to emphasize that the example provided in the preceding descriptions are meant only to be illustrative, and not exhaustive or exclusive of other technologies that fall into what are intended to be broad categories.